Neutrophils play an important role in intestinal inflammation by interacting with intestinal
epithelial cells. In this study, we evaluated neutrophil adhesion to intestinal epithelial cells …

Human hepatocyte expression of intercellular adhesion molecule-1 (ICAM-1)(CD54) was
studied in vitro by exposing the well differentiated human hepatoblastoma cell line HepG2 to …

The development of chronic liver diseases is mediated by sustained hepatic inflammation.
Our objective was to characterize the molecular mechanisms responsible for the hepatic …

Background: The interactions between polymorphonuclear neutrophils (PMNs) and
sinusoidal endothelial cells (SECs) have been known to be involved in the pathogenesis of …

Platelet endothelial cell adhesion molecule-1 (PECAM-1) is thought to be critical for
transendothelial migration of leukocytes, including neutrophils. Because neutrophil …

Communication circuits operating between activated monocytes/macrophages and adjacent
hepatocytes in the liver effect important alterations in hepatocyte function. We demonstrate …

Cholestasis-induced liver injury during bile duct obstruction causes an acute inflammatory
response. To further characterize the mechanisms underlying the neutrophil-induced cell …

Interactions between leukocytes such as T cells and accessory or target cells are promoted
by adhesion molecules, in particular intercellular adhesion molecule-1 (ICAM-1) and …

This study was designed to assess the effect of neutrophil inhibitory factor (NIF), a novel
specific inhibitor of CD11b/CD18 on hepatic leukocyte trafficking by intravital microscopy 5 h …

Neutrophil depleted mice are protected from concanavalin A-mediated hepatitis, showing
that neutrophils are critical for cellular liver damage. Interleukin-6 has pro-and anti …