Hepatic parenchymal cells respond in many different ways to acute-phase cytokines. Some
responses may protect against damage by liver-derived inflammatory mediators. Previous …

Abstract Systemically administered interleukin (IL)-12 causes liver inflammation in mice
characterized by Kupffer cell proliferation and hypertrophy, hepatocyte necrosis, and …

Crypt abscesses allow prolonged apposition of activated neutrophils to the epithelial surface
of the colon. Adhesion of neutrophils to both the vascular endothelium and basolateral …

Chronic alcohol intoxication has been associated with increased migration of inflammatory
leukocytes to the liver that may contribute to the development of alcoholic hepatitis in …

Transepithelial migration of neutrophils (PMN) is a defining characteristic of active
inflammatory states of mucosal surfaces. The process of PMN transepithelial migration …

Neutrophils are involved in organ damage induced by an excessive acute inflammatory
response after ischemia‐reperfusion, trauma, and sepsis. In addition to causing vascular …

Objective: Evolving evidence of anti-inflammatory effects is observed in patients with
rheumatoid arthritis or ulcerative colitis following periodic adsorptive granulocyte and …

Neutrophil-induced liver injury during endotoxemia is dependent on the adhesion molecule
Mac-1 (CD11b/CD18) on neutrophils. The potential involvement of its counterreceptor …

Complement activation is critical in the development of local mucosal damage and
inflammation as well as of remote organ injury after mesenteric ischemia/reperfusion. To …

Polymorphonuclear neutrophil (PMN) migration across epithelia is a common feature of
active inflammation. Given the suggested role of carbohydrates in this process, we …