Neuropsychiatric symptoms predict functional status in Alzheimer's disease

SC You, CM Walsh, LA Chiodo… - Journal of …, 2015 - content.iospress.com
Background: Cognitive deficits are presumed to be the primary driver of functional
impairment in Alzheimer's disease (AD); however, functional impairment is likely …

Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function

E Dale, AL Pehrson, T Jeyarajah, Y Li, SC Leiser… - CNS …, 2016 - cambridge.org
The hippocampus plays an important role in emotional and cognitive processing, and both
of these domains are affected in patients with major depressive disorder (MDD). Extensive …

Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease

Y Xu, J Yan, P Zhou, J Li, H Gao, Y Xia, Q Wang - Progress in neurobiology, 2012 - Elsevier
Cognitive dysfunction is one of the most typical characteristics in various neurodegenerative
diseases such as Alzheimer's disease and Parkinson's disease (advanced stage). Although …

The serotonergic system and cognitive function

D Švob Štrac, N Pivac, D Mück-Šeler - Translational neuroscience, 2016 - degruyter.com
Symptoms of cognitive dysfunction like memory loss, poor concentration, impaired learning
and executive functions are characteristic features of both schizophrenia and Alzheimer's …

Neurotransmitter deficits in behavioural and psychological symptoms of Alzheimer's disease

A Lanari, F Amenta, G Silvestrelli, D Tomassoni… - Mechanisms of ageing …, 2006 - Elsevier
Behavioural and psychological symptoms of dementia (BPSD) occur in 50–90% of
Alzheimer's disease (AD) patients. Imbalance of different neurotransmitters (acetylcholine …

Serotonin and brain function: a tale of two receptors

RL Carhart-Harris, DJ Nutt - Journal of psychopharmacology, 2017 - journals.sagepub.com
Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …

The neurobiology of neuropsychiatric syndromes in dementia

TW Meeks, SA Ropacki, DV Jeste - Current opinion in psychiatry, 2006 - journals.lww.com
Neuropsychiatric disturbances are a core feature of dementia and worsen many clinical
outcomes. Among the most validated syndromes are depression, psychosis, and sleep …

Neuropsychiatric symptoms in Alzheimer's disease

CG Lyketsos, MC Carrillo, JM Ryan… - Alzheimer's & …, 2011 - Elsevier
Neuropsychiatric symptoms (NPS) are core features of Alzheimer's disease and related
dementias. Once thought to emerge primarily in people with late-stage disease, these …

Serotonergic therapies for cognitive symptoms in Alzheimer's disease: rationale and current status

MJ Ramirez, MKP Lai, RM Tordera, PT Francis - Drugs, 2014 - Springer
Alzheimer's disease (AD) is the most common cause of dementia in elderly people.
Research focused on identifying compounds that restore cognition and memory in AD …

[图书][B] Cognitive neuropsychology of Alzheimer's disease

R Morris, J Becker - 2004 - books.google.com
Alzheimer's disease can be thought of as a multi-faceted neuropsychological disorder, with
diverse impairments in cognitive abilities, such as attention, memory, language and …