Divergent neuroimmune signatures in the cerebrospinal fluid predict differential gender-specific survival among patients with HIV-associated cryptococcal meningitis
Introduction Survival among people with HIV-associated cryptococcal meningitis (CM)
remains low, particularly among women, despite the currently optimal use of antifungal …
remains low, particularly among women, despite the currently optimal use of antifungal …
Cerebrospinal fluid cytokine profiles predict risk of early mortality and immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis
Understanding the host immune response during cryptococcal meningitis (CM) is of critical
importance for the development of immunomodulatory therapies. We profiled the …
importance for the development of immunomodulatory therapies. We profiled the …
Cerebrospinal fluid cytokine and chemokine patterns correlate with prognosis of HIV-uninfected cryptococcal meningitis: A prospective observational study
YK Jiang, RY Wang, LH Zhou, JH Cheng… - Frontiers in …, 2022 - frontiersin.org
The cerebrospinal fluid (CSF) immune responses in HIV-uninfected cryptococcal meningitis
(CM) have not been well studied. In this study, we aimed to explore the phenotype of CSF …
(CM) have not been well studied. In this study, we aimed to explore the phenotype of CSF …
Increased cryptococcal meningitis mortality among HIV negative, non-transplant patients: a single US center cohort study
G Motoa, A Pate, D Chastain, S Mann… - Therapeutic …, 2020 - journals.sagepub.com
Cryptococcal meningitis (CM) is an opportunistic fungal infection associated with human
immunodeficiency virus (HIV) and other forms of immunosuppression. We lack a clear …
immunodeficiency virus (HIV) and other forms of immunosuppression. We lack a clear …
The CSF Immune Response in HIV-1–Associated Cryptococcal Meningitis: Macrophage Activation, Correlates of Disease Severity, and Effect of Antiretroviral Therapy
JE Scriven, LM Graham, C Schutz… - JAIDS Journal of …, 2017 - journals.lww.com
Background: Immune modulation may improve outcome in HIV-associated cryptococcal
meningitis. Animal studies suggest alternatively activated macrophages are detrimental but …
meningitis. Animal studies suggest alternatively activated macrophages are detrimental but …
Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis
Background. Cryptococcal meningitis (CM) is a leading cause of HIV-associated mortality
globally. High fungal burden in cerebrospinal fluid (CSF) at diagnosis and poor fungal …
globally. High fungal burden in cerebrospinal fluid (CSF) at diagnosis and poor fungal …
HIV-associated cryptococcal meningitis occurring at relatively higher CD4 counts
Background Cryptococcal meningitis can occur in persons with less-apparent
immunosuppression. We evaluated clinical characteristics and outcomes of persons with …
immunosuppression. We evaluated clinical characteristics and outcomes of persons with …
A preliminary study on the characteristics of Th1/Th2 immune response in cerebrospinal fluid of AIDS patients with cryptococcal meningitis
A Li, W Zhu, J Yin, X Huang, L Sun, W Hua… - BMC Infectious …, 2021 - Springer
Abstract Background Cryptococcal Meningitis (CM) is a common opportunistic infection in
the late stage of acquired immunodeficiency syndrome (AIDS). Despite the wide use of …
the late stage of acquired immunodeficiency syndrome (AIDS). Despite the wide use of …
Determinants of mortality in a combined cohort of 501 patients with HIV-associated Cryptococcal meningitis: implications for improving outcomes
Background. Cryptococcal meningitis (CM) is a leading cause of death in individuals
infected with human immunodeficiency virus (HIV). Identifying factors associated with …
infected with human immunodeficiency virus (HIV). Identifying factors associated with …
Incidence, clinical presentation, and outcome of HIV-1-associated cryptococcal meningitis during the highly active antiretroviral therapy era: a nationwide cohort study
M Touma, LD Rasmussen, R Martin-Iguacel… - Clinical …, 2017 - Taylor & Francis
Background Human immunodeficiency virus (HIV) infection with advanced
immunosuppression predisposes to cryptococcal meningitis (CM). We describe the …
immunosuppression predisposes to cryptococcal meningitis (CM). We describe the …
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