Prolonged high-fat diets (HFDs) can cause intramyocellular lipid (IMCL) accumulation that
may negatively affect muscle function. We investigated the duration of a HFD required to …

Background and aims Increased adipose tissue may promote catabolic events in skeletal
muscle. The aim of this study was to test whether high-fat diet (HFD)-induced obesity would …

Obesity and ensuing disorders are increasingly prevalent in young populations. Prolonged
exposure to high-fat diets (HFD) and excessive lipid accumulation were recently suggested …

The phenotype of sarcopenic obesity is frequently associated with impaired muscle strength
and performance. Ectopic lipid deposition may interfere with muscle anabolic response …

Short‐term consumption of a high‐fat diet (HFD) can result in an oxidative shift in adult
skeletal muscle. However, the impact of HFD on young, growing muscle is largely unknown …

Background The effects of diet-induced obesity on skeletal muscle function are largely
unknown, particularly as it relates to changes in oxidative metabolism and morphology …

Aim: Both muscle mass and strength decline with ageing, but the loss of strength far
surpasses what is projected based on the decline in mass. Interestingly, the accumulation of …

Background A short-term high-fat diet impairs mitochondrial function and the ability of
skeletal muscle to respond to growth stimuli, but it is unknown whether such a diet alters the …

Obesity and inflammation are reportedly associated with the pathogenesis of sarcopenia,
which is characterized by age-related loss of skeletal muscle mass. Intramuscular fat …

Diet-induced obesity (DIO) is associated with glucose intolerance, insulin resistance (IR),
and an increase in intramyocellular lipids (IMCL), which may lead to disturbances in glucose …