[HTML][HTML] Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity
AK Anam, KM Cooke, MB Dratver, JV O'Bryan… - Molecular …, 2022 - Elsevier
Objective Maternal obesity increases the incidence of excess adiposity in newborns,
resulting in lifelong diabetes risk. Elevated intrauterine fetal adiposity has been attributed to …
resulting in lifelong diabetes risk. Elevated intrauterine fetal adiposity has been attributed to …
Maternal obesity modulates intracellular lipid turnover in the human term placenta
B Hirschmugl, G Desoye, P Catalano… - International journal of …, 2017 - nature.com
Background: Obesity before pregnancy is associated with impaired metabolic status of the
mother and the offspring later in life. These adverse effects have been attributed to …
mother and the offspring later in life. These adverse effects have been attributed to …
Effect of maternal obesity on placental lipid metabolism
V Calabuig-Navarro, M Haghiac, J Minium… - …, 2017 - academic.oup.com
Obese women, on average, give birth to babies with high fat mass. Placental lipid
metabolism alters fetal lipid delivery, potentially moderating neonatal adiposity, yet how it is …
metabolism alters fetal lipid delivery, potentially moderating neonatal adiposity, yet how it is …
[HTML][HTML] Effects of maternal obesity on placental function and fetal development
Obesity has reached epidemic proportions and pregnancies in obese mothers have
increased risk for complications including gestational diabetes, hypertensive disorders …
increased risk for complications including gestational diabetes, hypertensive disorders …
Role of insulin in placental transport of nutrients in gestational diabetes mellitus
M Ruiz-Palacios, AJ Ruiz-Alcaraz… - Annals of Nutrition and …, 2017 - karger.com
Background: Gestational diabetes mellitus (GDM) is associated with increased fetal
adiposity, which may increase the risk of obesity in adulthood. The placenta has insulin …
adiposity, which may increase the risk of obesity in adulthood. The placenta has insulin …
Placental fatty acid transport in maternal obesity
I Cetin, F Parisi, C Berti, C Mandò… - Journal of developmental …, 2012 - cambridge.org
Pregestational obesity is a significant risk factor for adverse pregnancy outcomes. Maternal
obesity is associated with a specific proinflammatory, endocrine and metabolic phenotype …
obesity is associated with a specific proinflammatory, endocrine and metabolic phenotype …
Altered maternal and placental lipid metabolism and fetal fat development in obesity: Current knowledge and advances in non-invasive assessment
F Delhaes, SA Giza, T Koreman, G Eastabrook… - Placenta, 2018 - Elsevier
Abnormal maternal lipid profiles, a hallmark of increased maternal adiposity, are associated
with pregnancy complications such as preeclampsia and gestational diabetes, and offspring …
with pregnancy complications such as preeclampsia and gestational diabetes, and offspring …
Placental function in maternal obesity
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
[HTML][HTML] Adipose tissue development and lipid metabolism in the human fetus: The 2020 perspective focusing on maternal diabetes and obesity
G Desoye, E Herrera - Progress in lipid research, 2021 - Elsevier
During development, the human fetus accrues the highest proportion of fat of all mammals.
Precursors of fat lobules can be found at week 14 of pregnancy. Thereafter, they expand …
Precursors of fat lobules can be found at week 14 of pregnancy. Thereafter, they expand …
Maternal obesity alters the placental transcriptome in a fetal sex-dependent manner
A Kelly, J Chan, TL Powell, LA Cox… - Frontiers in Cell and …, 2023 - frontiersin.org
Infants born to obese mothers have an increased risk of developing obesity and metabolic
diseases in childhood and adulthood. Although the molecular mechanisms linking maternal …
diseases in childhood and adulthood. Although the molecular mechanisms linking maternal …