Background Plasmodium falciparum gametocytes, specifically mature stages, are the only
stage in man transmissible to the mosquito vector responsible for malaria transmission. Anti …

Background Recent renewed emphasis on the eradication of malaria has highlighted the
need for more tools with which to achieve this ambitious goal. One high priority area is the …

Plasmodium falciparum gametocytes, specifically the mature stages, are the only malaria
parasite stage in humans transmissible to the mosquito vector. Anti-malarial drugs capable …

The discovery of new antimalarial drugs able to target both the asexual and gametocyte
stages of Plasmodium falciparum is critical to the success of the malaria eradication …

The design of new antimalarial combinations to treat Plasmodium falciparum infections
requires drugs that, in addition to resolving disease symptoms caused by asexual blood …

Objectives As most available antimalarial drugs are ineffective against the Plasmodium
falciparum transmission stages, new drugs against the parasite's gametocytes are urgently …

Drugs that kill or inhibit the sexual stages of Plasmodium in order to prevent transmission
are important components of malaria control programmes. Reducing gametocyte carriage is …

Malaria elimination will require interventions that prevent parasite transmission from the
human host to the mosquito. Experimentally, this is usually determined by the expensive and …

It is the mature gametocytes of Plasmodium that are solely responsible for parasite
transmission from the mammalian host to the mosquito. They are therefore a logical target …

Background The discovery of malaria transmission-blocking compounds is seen as key to
malaria elimination strategies and gametocyte-screening platforms are critical filters to …