Defining causality between an agent-be it a virus, bacteria, or chemical—and a disease is
the principal aim of biomedical research. Achievement of this lofty goal is hampered when …

Human cytomegalovirus (HCMV) was first isolated 50 years ago, when the new technology
of cell culture became available. The pathogenesis of HCMV disease is complex, involving …

Human cytomegalovirus (HCMV) is a human pathogen that infects greater than 50% of the
human population. HCMV infection is usually asymptomatic in most individuals. That is …

In this book the current knowledge on human cytomegalovirus (HCMV) as a human
pathogen is lucidly summarized, bringing the reader fully up to date with current knowledge …

Human cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft
recipient and AIDS patients. More recently, it has been recognized as a pathogen for those …

Human cytomegalovirus (HCMV) is a ubiquitous human persistent virus, which causes
disease particularly in the setting of immunosuppression. This review deals with aspects of …

As with all herpesviruses, human cytomegalovirus (HCMV) can establish lifelong
persistence after primary infection, with reactivation occurring often as a result of …

Two distinct processes contribute to the spectrum of human cytomegalovirus (HCMV)-
induced pathology. In the first instance, cytopathic effects appear to occur as a direct result of …

The mechanism (s) of pathogenesis caused by persistent viruses such as the human
cytomegalovirus (HCMV) are strongly associated with the control of transcription. In this …

Infections with human cytomegalovirus (HCMV) are a major cause of morbidity and mortality
in humans with acquired or developmental deficits in innate and adaptive immunity. In the …