Hypertension as a predictive marker for bevacizumab in metastatic breast cancer: results from a retrospective matched-pair analysis
SP Gampenrieder, F Romeder, C MUß… - Anticancer …, 2014 - ar.iiarjournals.org
Background: Several phase-III studies have shown improvements in terms of progression-
free survival (PFS) with bevacizumab when added to chemotherapy in advanced breast …
free survival (PFS) with bevacizumab when added to chemotherapy in advanced breast …
An observational study of bevacizumab‐induced hypertension as a clinical biomarker of antitumor activity
O Mir, R Coriat, L Cabanes, S Ropert… - The …, 2011 - academic.oup.com
Background. Hypertension is a common toxicity of bevacizumab, but the frequency of
assessment of blood pressure and standardized grading remain to be defined. This study …
assessment of blood pressure and standardized grading remain to be defined. This study …
Increased risk of high-grade hypertension with bevacizumab in cancer patients: a meta-analysis
V Ranpura, B Pulipati, D Chu, X Zhu… - American journal of …, 2010 - academic.oup.com
Background Hypertension is associated with the use of bevacizumab, an angiogenesis
inhibitor widely used in cancer therapy. Currently, the risk of severe hypertension associated …
inhibitor widely used in cancer therapy. Currently, the risk of severe hypertension associated …
Magnitude of risks and benefits of the addition of bevacizumab to chemotherapy for advanced breast cancer patients: Meta-regression analysis of randomized trials
F Cuppone, E Bria, V Vaccaro, F Puglisi, A Fabi… - Journal of Experimental …, 2011 - Springer
Background Although the addition of bevacizumab significantly improves the efficacy of
chemotherapy for advanced breast cancer, regulatory concerns still exist with regard to the …
chemotherapy for advanced breast cancer, regulatory concerns still exist with regard to the …
Analysis of early hypertension (HTN) and clinical outcome with bevacizumab (BV).
H Hurwitz, PS Douglas, JP Middleton… - Journal of Clinical …, 2010 - ascopubs.org
3039 Background: HTN is associated with anti-VEGF treatment (Tx), but this association has
not been well studied. To assess the prognostic and predictive importance of BV-related …
not been well studied. To assess the prognostic and predictive importance of BV-related …
Renovascular safety of bevacizumab in breast cancer patients. The prognostic value of hypertension and proteinuria
V Launay-Vacher, N Janus, P Beuzeboc… - Bulletin du …, 2015 - europepmc.org
Methods Patients from 8 centres were included between 2009 and 2011 with a follow-up of
1 year. They were naive of any previous anti-VEGF treatment and planned to be started on …
1 year. They were naive of any previous anti-VEGF treatment and planned to be started on …
Hypertension as a surrogate marker for the activity of anti-VEGF agents
O Mir, S Ropert, J Alexandre… - Annals of …, 2009 - annalsofoncology.org
found that the occurrence of hypertension [grade‡ 3 according to the National Cancer
Institute—Common Toxicity Criteria (NCI-CTC)[13]] was associated with a higher response …
Institute—Common Toxicity Criteria (NCI-CTC)[13]] was associated with a higher response …
Hypertension and proteinuria as predictive factors of effects of bevacizumab on advanced breast cancer in Japan
H Tanaka, K Takahashi, K Yamaguchi… - Biological and …, 2018 - jstage.jst.go.jp
Bevacizumab (BV), an inhibitor of vascular endothelial growth factor, is used in combination
with paclitaxel (PTX) to treat advanced breast cancer. Hypertension and proteinuria are …
with paclitaxel (PTX) to treat advanced breast cancer. Hypertension and proteinuria are …
[HTML][HTML] First-line bevacizumab-containing therapy for breast cancer: results in patients aged≥ 70 years treated in the ATHENA study
L Biganzoli, E Di Vincenzo, Z Jiang, M Lichinitser… - Annals of oncology, 2012 - Elsevier
Background There are limited data on treatment outcomes in the growing population of
elderly patients with locally recurrent/metastatic breast cancer (LR/mBC). To gain …
elderly patients with locally recurrent/metastatic breast cancer (LR/mBC). To gain …
Analysis of early hypertension and clinical outcome with bevacizumab: results from seven phase III studies
HI Hurwitz, PS Douglas, JP Middleton… - The …, 2013 - academic.oup.com
Background. Hypertension is associated with antivascular endothelial growth factor
treatment, but the clinical implications of hypertension are uncertain. To assess the …
treatment, but the clinical implications of hypertension are uncertain. To assess the …