The circadian system of mammals is composed of a hierarchy of oscillators that function at
the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell …

In mammals, the suprachiasmatic nuclei (SCN) of the hypothalamus act as a dominant
circadian pacemaker, coordinating rhythms throughout the body and regulating daily and …

The mammalian circadian system, which is comprised of multiple cellular clocks located in
the organs and tissues, orchestrates their regulation in a hierarchical manner throughout the …

Daily and seasonal rhythms in the endocrine system are co-ordinated by a hypothalamic
pacemaker, the suprachiasmatic nuclei (SCN) that is synchronised to solar time by direct …

Although circadian rhythms in mammalian physiology and behavior are dependent upon a
biological clock in the suprachiasmatic nuclei (SCN) of the hypothalamus, the molecular …

Compelling reasons to study the role of sex in the circadian system include the higher rates
of sleep disorders in women than in men and evidence that sex steroids modulate circadian …

Circadian timing affects almost all life's processes. It not only dictates when we sleep, but
also keeps every cell and tissue working under a tight temporal regimen. The daily …

Circadian rhythms are physiological and behavioral processes that exhibit a 24‐hr cycle.
These daily rhythms are essential for living organisms to align their behavior and physiology …

Female reproduction requires the precise temporal organization of interacting, estradiol-
sensitive neural circuits that converge to optimally drive hypothalamo-pituitary–gonadal …

Humans and other mammalian species possess an endogenous circadian clock system that
has evolved in adaptation to periodically reoccurring environmental changes and drives …