Background: Cancer vaccines are a unique approach to cancer therapy. They exert an
antitumor effect by engaging the host immune response, and have great potential for …

Cancer vaccines are at the forefront of novel, targeted approaches to cancer treatment. Low
toxicity, the potential for circumventing drug cross-resistance, and the potential for …

In this editorial, we highlight articles published in this Special Issue of Vaccines on “Cancer
Vaccines and Immunotherapy for Tumor Prevention and Treatment”, recent developments in …

The first generation of human cancer vaccines has been tested in phase III clinical trials, but
only a few of these have demonstrated sufficient efficacy to be licensed for clinical use. This …

Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results …

Cancer vaccines have been shown clinically to drive tumor-reactive cell activation,
proliferation, and effector function. Unfortunately, tumor eradication by treatment with cancer …

Designing cancer vaccines has been at the forefront of cancer research for over two-and-a-
half decades. In particular, delivery methods used to stimulate effective and long-lasting …

There are strong biologic and preclinical rationales for the development of therapeutic
cancer vaccines; however, the clinical translation of this treatment strategy has been …

Therapeutic cancer vaccines have the potential of being integrated in the therapy of
numerous cancer types and stages. The wide spectrum of vaccine platforms and vaccine …

The advent of cancer immunotherapy has revolutionized the field of cancer treatment and
offers cancer patients new hope. Although this therapy has proved highly successful for …