[HTML][HTML] Hypothalamic neurons that regulate feeding can influence sleep/wake states based on homeostatic need
N Goldstein, BJ Levine, KA Loy, WL Duke… - Current Biology, 2018 - cell.com
Eating and sleeping represent two mutually exclusive behaviors that satisfy distinct
homeostatic needs. Because an animal cannot eat and sleep at the same time, brain …
homeostatic needs. Because an animal cannot eat and sleep at the same time, brain …
[HTML][HTML] Identification of neurons with a privileged role in sleep homeostasis in Drosophila melanogaster
Sleep is thought to be controlled by two main processes: a circadian clock that primarily
regulates sleep timing and a homeostatic mechanism that detects and responds to sleep …
regulates sleep timing and a homeostatic mechanism that detects and responds to sleep …
Chronic sleep restriction disrupts sleep homeostasis and behavioral sensitivity to alcohol by reducing the extracellular accumulation of adenosine
J Clasadonte, SR McIver, LI Schmitt… - Journal of …, 2014 - Soc Neuroscience
Sleep impairments are comorbid with a variety of neurological and psychiatric disorders
including depression, epilepsy, and alcohol abuse. Despite the prevalence of these …
including depression, epilepsy, and alcohol abuse. Despite the prevalence of these …
Wake–sleep circuitry: an overview
CB Saper, PM Fuller - Current opinion in neurobiology, 2017 - Elsevier
Highlights•Glutamatergic neurons in the parabrachial nucleus provide main ascending
arousal influence from the brainstem.•GABAergic neurons in the brainstem provide the main …
arousal influence from the brainstem.•GABAergic neurons in the brainstem provide the main …
A global brain state underlies C. elegans sleep behavior
ALA Nichols, T Eichler, R Latham, M Zimmer - Science, 2017 - science.org
INTRODUCTION Global brain states such as sleep and wakefulness involve
reconfigurations of neural circuit activity across the entire nervous system. Yet it is not …
reconfigurations of neural circuit activity across the entire nervous system. Yet it is not …
Activation of ventral tegmental area dopamine neurons produces wakefulness through dopamine D2-like receptors in mice
Y Oishi, Y Suzuki, K Takahashi, T Yonezawa… - Brain Structure and …, 2017 - Springer
A growing body of evidence suggests that dopamine plays a role in sleep–wake regulation,
but the dopamine-producing brain areas that control sleep–wake states are unclear. In this …
but the dopamine-producing brain areas that control sleep–wake states are unclear. In this …
Adenosine and sleep–wake regulation
This review addresses three principal questions about adenosine and sleep–wake
regulation:(1) Is adenosine an endogenous sleep factor?(2) Are there specific brain regions …
regulation:(1) Is adenosine an endogenous sleep factor?(2) Are there specific brain regions …
Adenosine and the homeostatic control of sleep: effects of A1 receptor blockade in the perifornical lateral hypothalamus on sleep–wakefulness
MM Thakkar, SC Engemann, KM Walsh, PK Sahota - Neuroscience, 2008 - Elsevier
The orexinergic neurons of the lateral hypothalamus (LH) are critical for wakefulness
[McCarley RW (2007) Neurobiology of REM and NREM sleep. Sleep Med 8: 302–330] …
[McCarley RW (2007) Neurobiology of REM and NREM sleep. Sleep Med 8: 302–330] …
VTA dopaminergic neurons regulate ethologically relevant sleep–wake behaviors
Dopaminergic ventral tegmental area (VTA) neurons are critically involved in a variety of
behaviors that rely on heightened arousal, but whether they directly and causally control the …
behaviors that rely on heightened arousal, but whether they directly and causally control the …