Publisher Summary Investigations examining the pathogenesis and therapy of experimental
disseminated Candida infection have been performed by using a various animals models …

Publisher Summary This chapter focuses on the rodent models of candida sepsis. Of the
various types of animal used to study disseminated candidosis, mouse is the most popular …

Animal models are powerful tools to study the pathogenesis of diverse types of candidiasis.
Murine models are particularly attractive because of cost, ease of handling, technical …

Endocarditis caused by Candida albicans was induced in rabbits after insertion of a catheter
across the aortic valve. The mean survival time of 34 rabbits was 26 days. Only 7% of …

The intravenous challenge model of Candida albicans infection in mice is a well-established
procedure that mirrors disseminated candidiasis in humans. In this model, in which the …

A reproducible model of a generalized Candida albicans infection was established in rats to
allow a precise evaluation of the efficacy of antifungal compounds. In contrast to the …

The mouse intravenous (IV) challenge model of Candida albicans invasive fungal infection
has been widely used to study the importance of the innate immune system in these …

Members of the genus Candida, particularly C. albicans, are frequent human pathogens that
have increased in importance with advances in modern medicine and chemotherapy …

Candida pathogenesis was examined by intravenous challenge of mice with either C.
albicans or C. guilliermondii. Animals were moribund 12 h postchallenge with C. albicans …

Candida endocarditis. It provides both access routes for invading Candida and suitable
endocardial foci on which the circulating Candida can implant. There are many possible …