AML with translocation t (8; 16)(p11; p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features
T Haferlach, A Kohlmann, HU Klein, C Ruckert… - Leukemia, 2009 - nature.com
Balanced chromosomal rearrangements define distinct entities in acute myeloid leukemia
(AML). Here, we present 13 AML cases with t (8; 16)(p11; p13) with observed low incidence …
(AML). Here, we present 13 AML cases with t (8; 16)(p11; p13) with observed low incidence …
Cytogenetic profile in de novo acute myeloid leukemia with FAB subtypes M0, M1, and M2: a study based on 652 cases analyzed with morphology, cytogenetics, and …
M Klaus, T Haferlach, S Schnittger, W Kern… - Cancer Genetics and …, 2004 - Elsevier
In about 55% of acute myeloid leukemia (AML) cases, chromosome aberrations are
detectable by cytogenetics. Close correlations between cytomorphology and cytogenetics …
detectable by cytogenetics. Close correlations between cytomorphology and cytogenetics …
Characteristics of t (8; 21) acute myeloid leukemia (AML) with additional chromosomal abnormality: concomitant trisomy 4 may constitute a distinctive subtype of t (8; …
K Nishii, E Usui, N Katayama, V Lorenzo, K Nakase… - Leukemia, 2003 - nature.com
Abstract t (8; 21)(q22; q22) is the most frequently observed karyotypic abnormality
associated with acute myeloid leukemia (AML), especially in FAB M2. Clinically, this type of …
associated with acute myeloid leukemia (AML), especially in FAB M2. Clinically, this type of …
Acute myeloid leukemia with recurrent cytogenetic abnormalities
K Foucar, J Anastasi - American Journal of Clinical Pathology, 2015 - academic.oup.com
Abstract Objectives: Session 1 of the 2013 Society for Hematopathology/European
Association for Hematopathology Workshop was devoted to the cases of acute myeloid …
Association for Hematopathology Workshop was devoted to the cases of acute myeloid …
AML with 11q23/MLL abnormalities as defined by the WHO classification: incidence, partner chromosomes, FAB subtype, age distribution, and prognostic impact in …
C Schoch, S Schnittger, M Klaus, W Kern… - Blood, 2003 - ashpublications.org
Acute myeloid leukemia (AML) cases with 11q23 abnormalities involving the MLL gene
comprise one category of recurring genetic abnormalities in the WHO classification. In an …
comprise one category of recurring genetic abnormalities in the WHO classification. In an …
Acute myeloid leukemias with reciprocal rearrangements can be distinguished by specific gene expression profiles
C Schoch, A Kohlmann, S Schnittger… - Proceedings of the …, 2002 - National Acad Sciences
Acute myeloid leukemia (AML) is a heterogeneous group of genetically defined diseases.
Their classification is important with regard to prognosis and treatment. We performed …
Their classification is important with regard to prognosis and treatment. We performed …
Philadelphia chromosome-positive acute myeloid leukemia: cytoimmunologic and cytogenetic features
A Cuneo, A Ferrant, JL Michaux, H Demuynck… - …, 1996 - haematologica.org
BACKGROUND: Little is known about the morphological and clinical features of the minority
of acute myeloid leukemias (AML) that carry the t (9; 22)(q34; q11) translocation …
of acute myeloid leukemias (AML) that carry the t (9; 22)(q34; q11) translocation …
Acute myeloid leukemia associated with variant t (8; 21) detected by conventional cytogenetic and molecular studies: a report of four cases and review of the literature
L Huang, LV Abruzzo, JR Valbuena… - American journal of …, 2006 - academic.oup.com
Acute myeloid leukemia (AML) with the t (8; 21)(q22; q22) creating the AML1-ETO fusion
gene is a distinct type of AML generally associated with a favorable prognosis. The …
gene is a distinct type of AML generally associated with a favorable prognosis. The …
Clinical importance of cytogenetics in acute myeloid leukaemia
K Mrózek, K Heinonen, CD Bloomfield - Best Practice & Research Clinical …, 2001 - Elsevier
Acquired chromosome aberrations are present in the marrow of most patients with acute
myeloid leukaemia (AML) at diagnosis. Cytogenetically, AML is a very heterogeneous …
myeloid leukaemia (AML) at diagnosis. Cytogenetically, AML is a very heterogeneous …
Acute myeloid leukemia with translocation t (8; 16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis
A Diab, L Zickl, O Abdel-Wahab, S Jhanwar… - Leukemia research, 2013 - Elsevier
Previous small series have suggested that acute myeloid leukemia with t (8; 16) is a distinct
morphologic and clinical entity associated with poor prognosis. We describe 18 patients with …
morphologic and clinical entity associated with poor prognosis. We describe 18 patients with …