Recent advances of pyridinone in medicinal chemistry
S Lin, C Liu, X Zhao, X Han, X Li, Y Ye, Z Li - Frontiers in Chemistry, 2022 - frontiersin.org
Pyridinones have been adopted as an important block in medicinal chemistry that could
serve as hydrogen bond donors and acceptors. With the help of feasible synthesis routes via …
serve as hydrogen bond donors and acceptors. With the help of feasible synthesis routes via …
Recent insights about pyrrolidine core skeletons in pharmacology
S Poyraz, HA Döndaş, NY Döndaş… - Frontiers in …, 2023 - frontiersin.org
To overcome numerous health disorders, heterocyclic structures of synthetic or natural origin
are utilized, and notably, the emergence of various side effects of existing drugs used for …
are utilized, and notably, the emergence of various side effects of existing drugs used for …
Pyridazine based scaffolds as privileged structures in anti-cancer therapy
MY Jaballah, RT Serya, K Abouzid - Drug Research, 2017 - thieme-connect.com
Pyridazines, their oxo derivatives; pyridazinone as well as fused bi-or tricyclic pyridazine
containing scaffolds are key structural features of many biologically active compounds with …
containing scaffolds are key structural features of many biologically active compounds with …
Pyridones in drug discovery: Recent advances
Y Zhang, A Pike - Bioorganic & Medicinal Chemistry Letters, 2021 - Elsevier
Pyridones have been utilized as privileged scaffolds in drug discovery. Some of the
important roles where this class of heterocycles have found utility in medicinal chemistry …
important roles where this class of heterocycles have found utility in medicinal chemistry …
Pyridine: the scaffolds with significant clinical diversity
The nitrogen-bearing heterocycle pyridine in its several analogous forms occupies an
important position as a precious source of clinically useful agents in the field of medicinal …
important position as a precious source of clinically useful agents in the field of medicinal …
A comprehensive review on pyrimidine analogs-versatile scaffold with medicinal and biological potential
J Basha, NM Goudgaon - Journal of Molecular Structure, 2021 - Elsevier
Pyrimidines are nitrogen-containing heterocycles known for anticancer, anti-HIV, antifungal,
and antibacterial activities. Pyrimidines, compounds bearing this heterocycle, are common …
and antibacterial activities. Pyrimidines, compounds bearing this heterocycle, are common …
Bioactive pyrrole-based compounds with target selectivity
GL Petri, V Spano, R Spatola, R Holl… - European journal of …, 2020 - Elsevier
The discovery of novel synthetic compounds with drug-like properties is an ongoing
challenge in medicinal chemistry. Natural products have inspired the synthesis of …
challenge in medicinal chemistry. Natural products have inspired the synthesis of …
Pyridazine as a privileged structure: An updated review on anticancer activity of pyridazine containing bioactive molecules
ZX He, YP Gong, X Zhang, LY Ma, W Zhao - European journal of medicinal …, 2021 - Elsevier
Identification of potent anticancer agents with high selectivity and low toxicity remains on the
way to human health. Pyridazine featuring advantageous physicochemical properties and …
way to human health. Pyridazine featuring advantageous physicochemical properties and …
Pyrrole: An insight into recent pharmacological advances with structure activity relationship
Pyrrole is a heterocyclic ring template with multiple pharmacophores that provides a way for
the generation of library of enormous lead molecules. Owing to its vast pharmacological …
the generation of library of enormous lead molecules. Owing to its vast pharmacological …
Recent medicinal approaches of novel pyrimidine analogs: A review
SB Patil - Heliyon, 2023 - cell.com
Pyrimidine derivatives attract researchers due to their versatile scaffold & their medicinal
significance. Pyrimidine associated analogs are majorly contributed to the field of medicinal …
significance. Pyrimidine associated analogs are majorly contributed to the field of medicinal …