Molecular‐dynamics simulations of amyloid‐β1–42 peptides including d‐aspartic acid
residues were performed, and their three‐dimensional structures were compared. The …

Fibrillated aggregation of amyloid β (Aβ) peptides is a potential factor causing toxic amyloid
deposition in neurodegenerative diseases. A toxic fibril formation of Aβ is known to be …

Amyloid β-peptide (Aβ) is the major component of plaques found in the brains of Alzheimer's
patients. Among its two predominate forms− Aβ (1–40) and Aβ (1–42), the latter possesses …

To study the folding/unfolding properties of a β-amyloid peptide Aβ12–36 of Alzheimer's
disease, five molecular dynamics simulations of Aβ12–36 in explicit water were done at 450 …

The amyloid β-peptides (Aβs), containing 39–43 residues, are the key protein components
of amyloid deposits in Alzheimer's disease. To structurally characterize the dynamic …

Accumulation of the amyloid beta (Aβ) peptide in the brain is responsible for debilitating
neurodegenerative diseases, such as Alzheimer's disease (AD). We have carried out …

Molecular dynamics simulations of amyloid β1–42 containing d-aspartic acid residues were
performed using several continuous solvent models to investigate the usefulness of …

Abstract The amyloid Aβ (1–40) peptide of Alzheimer's disease was chosen as model
compound. This Aβ peptide is an intrinsically soluble peptide; the C-terminal amino acids …

To study the early stage of amyloid‐β peptide (Aβ) aggregation, hexamers of the wild‐type
(WT) Aβ16–35 and its mutants with amyloid‐like conformations have been studied by …

β-Amyloid peptides are believed to play an essential role in Alzheimer's disease (AD), due
to their sedimentation in the form of β-amyloid aggregates in the brain of AD-patients, and …