Lessons from animal experiments in myocarditis.

A Matsumori - Herz, 1992 - europepmc.org
We have developed murine models of viral myocarditis induced by encephalomyocarditis
(EMC) virus in which severe myocarditis, congestive heart failure and dilated …

Immunomodulating agents for the management of heart failure with myocarditis and cardiomyopathy—lessons from animal experiments

A Matsumori, S Sasayama - European heart journal, 1995 - academic.oup.com
We have developed murine models of viral myocarditis induced by the
encephalomyocarditis (EMC) virus in which there is a high incidence of severe myocarditis …

Comparison of angiotensin converting enzyme inhibition and angiotensin II receptor blockade for the prevention of experimental autoimmune myocarditis

TJ Bahk, MD Daniels, JS Leon, K Wang… - International journal of …, 2008 - Elsevier
The angiotensin converting enzyme inhibitor captopril prevents myosin-induced
experimental autoimmune myocarditis. Captopril inhibits production of angiotensin II and …

Effect of indomethacin in the late phase of coxsackievirus myocarditis in a murine model

S Rezkalla, R Khatib, G Khatib, F Smith… - The Journal of …, 1988 - translationalres.com
Previous studies have shown that indomethacin administered during the early phase of
experimental myocarditis may exacerbate the disease process. It is unknown whether late …

Experimental murine model for autoimmune myocarditis using Klebsiella pneumoniae O3 lipopolysaccharide as a potent immunological adjuvant

N Kato, Y Fujii, N Agata, N Kido, M Ohta, S Naito… - …, 1993 - Taylor & Francis
Experimental autoimmune myocarditis could be produced in mice by repeated injection of
syngeneic heart extract together with Klebsiella pneumoniae O3 lipopolysaccharide (KO3 …

A nonsteroid anti-inflammatory drug exacerbates Coxsackie B3 murine myocarditis

MR Costanzo-Nordin, EA Reap, JB O'connell… - Journal of the American …, 1985 - Elsevier
Nonsteroid anti-inflammatory drugs are often used to treat myalgias and arthralgias in
enteroviral infections, but their effects on acute viral myocarditis are unknown. The effect of …

Immunomodulating factors and immunosuppressive drugs in the therapy of myocarditis.

B Maisch, M Herzum, U Schönian - Scandinavian journal of …, 1993 - europepmc.org
This review examines the immunologic rationale for immunosuppressive and
immunomodulating therapy in man and experimental animal. The controversy if …

Rat dilated cardiomyopathy after autoimmune giant cell myocarditis.

M Kodama, H Hanawa, M Saeki, H Hosono… - Circulation …, 1994 - Am Heart Assoc
One of the possible causes of dilated cardiomyopathy is considered to be a sequel to
myocarditis. Two mechanisms have been proposed in the process of progression of …

[PDF][PDF] Experimental autoimmune myocarditis

M Kodama, T Izumi - Acta Med Biol, 1991 - niigata-u.repo.nii.ac.jp
Recently, we have established a novel experimental model for autoimmune myocarditis.
Acute serious myocarditis can be induced in Lewis rats by immunization with cardiac …

In vivo lymphocyte-mediated myocardial injuries demonstrated by adoptive transfer of experimental autoimmune myocarditis.

M Kodama, Y Matsumoto, M Fujiwara - Circulation, 1992 - Am Heart Assoc
BACKGROUND To elucidate the mechanisms of immune-related myocardial injuries, we
examined whether autoimmune myocarditis was passively transferable by use of humoral or …