The renin-angiotensin system is primarily responsible for regulating vascular tone. Drugs
that inhibit this pathway, angiotensin-converting enzyme inhibitors and angiotensin receptor …

Using the murine model of coxsackievirus B3-induced myocarditis we studied the effects of
various immunosuppressive agents on the course and outcome of the disease in genetically …

Regardless of the origin, injury to the heart can result in cardiomyocyte hypertrophy, fibrosis,
and cell death. Myocarditis often progresses to dilated cardiomyopathy (DCM), a major …

The most important clinical manifestation of myocarditis is congestive heart failure. The
precise mechanisms of heart failure during myocarditis have not been elucidated because …

Background Autoimmune mechanisms have been implicated in the pathogenesis of chronic
ongoing myocarditis. To investigate this relation, we used an A/J mouse model inoculated …

The hypothesis that viral infections may induce immunologically-mediated chronic
myocardial damage which culminates in symptomatic congestive heart failure has achieved …

Background—Autoimmunity to cardiac antigens, in particular cardiac myosin, has been
observed in humans with myocarditis and in animals with experimental inflammatory heart …

Experimental autoimmune myocarditis (EAM) in rats is a T‐cell‐mediated disorder and has
been shown to involve immune imbalance. The aim of this study was to examine the …

Serial technetium-99m radionuclide ventriculograms, indium-111 antimyosin antibody scans
and tissue biodistribution studies were performed in C, H/He mice with experimentally …

OBJECTIVE: Experimental autoimmune myocarditis (EAM) in rats is a T cell-mediated
disorder and the involvement of Th1/Th2 unbalance has been demonstrated. This study was …