[HTML][HTML] Yes-associated protein expression is correlated to the differentiation of prostate adenocarcinoma
Background Yes-associated protein (YAP) in the Hippo signaling pathway is a growth
control pathway that regulates cell proliferation and stem cell functions. Abnormal regulation …
control pathway that regulates cell proliferation and stem cell functions. Abnormal regulation …
YAP1 is involved in tumorigenic properties of prostate cancer cells
Abstract The Yes Associated Protein 1 (YAP1) is a transcriptional cofactor negatively
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …
Role of Yes-associated protein in cancer: An update
R Abylkassov, Y Xie - Oncology letters, 2016 - spandidos-publications.com
Yes-associated protein (YAP) is an oncoprotein located in the cytoplasm in an inactive form,
and when activated, it translocates to the nucleus and activates the transcription of genes …
and when activated, it translocates to the nucleus and activates the transcription of genes …
YAP is overexpressed in clear cell renal cell carcinoma and its knockdown reduces cell proliferation and induces cell cycle arrest and apoptosis
JJ Cao, XM Zhao, DL Wang, KH Chen… - Oncology …, 2014 - spandidos-publications.com
Yes-associated protein (YAP) has been reported to be an oncogene in a number of
malignancies. It constitutes an important regulatory mechanism for the Hippo pathway, a key …
malignancies. It constitutes an important regulatory mechanism for the Hippo pathway, a key …
[HTML][HTML] Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension
Objective: Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …
[HTML][HTML] YAP knockdown inhibits proliferation and induces apoptosis of human prostate cancer DU145 cells
X Jin, W Zhao, P Zhou, T Niu - Molecular medicine …, 2018 - spandidos-publications.com
The role of yes-associated protein (YAP) in human prostate cancer DU145 cells and its
underlying molecular mechanisms were explored in the present study. Initially, the …
underlying molecular mechanisms were explored in the present study. Initially, the …
Loss of YAP protein in prostate cancer is associated with Gleason score increase
X Hu, Y Jia, J Yu, J Chen, Q Fu - Tumori Journal, 2015 - journals.sagepub.com
Aims and Background To investigate the expression of YAP protein by
immunohistochemistry in prostate cancer tissues and hyperplasia or normal prostate tissues …
immunohistochemistry in prostate cancer tissues and hyperplasia or normal prostate tissues …
[HTML][HTML] Yes-associated protein promotes tumour development in luminal epithelial derived breast cancer
X Wang, L Su, Q Ou - European journal of cancer, 2012 - Elsevier
Yes-associated protein (YAP) is inactivated by the tumour suppressing Hippo pathway. The
YAP gene is amplified in human liver cancer, and promotes tumour growth. However, there …
YAP gene is amplified in human liver cancer, and promotes tumour growth. However, there …
Overexpression of yes‐associated protein contributes to progression and poor prognosis of non‐small‐cell lung cancer
Yes‐associated protein (YAP), the nuclear effector of the Hippo pathway, is a key regulator
of organ size and a candidate human oncogene. This study aimed to assess the clinical …
of organ size and a candidate human oncogene. This study aimed to assess the clinical …
Clinical and prognostic significance of Yes-associated protein in colorectal cancer
Y Wang, C Xie, Q Li, K Xu, E Wang - Tumor Biology, 2013 - Springer
The Hippo signaling pathway is a critical regulator of organ size control during development,
and its deregulation is associated with cancers. Acting downstream of this pathway, Yes …
and its deregulation is associated with cancers. Acting downstream of this pathway, Yes …