The pharmacophore concept in modern drug research is highlighted and the most important
use examples and success stories are reviewed. These include papers from method …

This review highlights the concept of using pharmacophore models in modern drug research
and reviews some important examples as well as success stories. This includes papers from …

Background: The pharmacophore concept in modern drug research is of great importance
and promotes the development of drug industry as indicated by the number of publications …

Computer-aided drug discovery techniques reduce the time and the costs needed to
develop novel drugs. Their relevance becomes more and more evident with the needs due …

Computational design of molecules with desired properties has become indispensable in
many areas of research, particularly in the pharmaceutical industry and academia …

Pharmacophore-based techniques currently are an integral part of many computer-aided
drug design workflows and have been successfully and extensively applied for tasks such …

A pharmacophore is a model which represents the key physico-chemical interactions that
mediate biological activity. There is a long history of using pharmacophore modeling …

This review summarizes the background and updated progress of pharmacophore based
drug design and provides the fundamental approach strategies on both structure based and …

The pharmacophore concept is of central importance in computer-aided drug design
(CADD) mainly because of its successful application in medicinal chemistry and, in …

Pharmacophore approaches have become one of the major tools in drug discovery after the
past century's development. Various ligand-based and structure-based methods have been …