Optimized glucocorticoid therapy: teaching old drugs new tricks
C Strehl, F Buttgereit - Molecular and cellular endocrinology, 2013 - Elsevier
Glucocorticoids (GCs) are commonly used in the treatment of a wide range of rheumatic and
other inflammatory diseases. They exert their potent anti-inflammatory and …
other inflammatory diseases. They exert their potent anti-inflammatory and …
[PDF][PDF] Pharmacodynamics of glucocorticoids
C Strehl, CM Spies, F Buttgereit - Clinical and Experimental …, 2011 - clinexprheumatol.org
Exogenous glucocorticoids (GCs) are used as anti-inflammatory and immunosuppressive
drugs in the treatment of a wide range of rheumatic and other inflammatory diseases. GCs …
drugs in the treatment of a wide range of rheumatic and other inflammatory diseases. GCs …
Glucocorticoids' pharmacology: past, present and future
Glucocorticoids (GCs) constitute the most important and widely prescribed class of anti-
inflammatory and immunosuppressive drugs. Since their first clinical use more than half a …
inflammatory and immunosuppressive drugs. Since their first clinical use more than half a …
Therapeutic mechanisms of glucocorticoids
J Vandewalle, A Luypaert, K De Bosscher… - Trends in Endocrinology & …, 2018 - cell.com
Glucocorticoids (GCs) have been used clinically for decades as potent anti-inflammatory
and immunosuppressive agents. Nevertheless, their use is severely hampered by the risk of …
and immunosuppressive agents. Nevertheless, their use is severely hampered by the risk of …
Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists
C Stahn, M Löwenberg, DW Hommes… - Molecular and cellular …, 2007 - Elsevier
Glucocorticoids (GC) are the most common used anti-inflammatory and immunosuppressive
drugs in the treatment of rheumatic and other inflammatory diseases. Their therapeutic …
drugs in the treatment of rheumatic and other inflammatory diseases. Their therapeutic …
Minireview: latest perspectives on antiinflammatory actions of glucocorticoids
K De Bosscher, G Haegeman - Molecular endocrinology, 2009 - academic.oup.com
Taking into consideration that glucocorticoid (GC) hormones have been used clinically for
over half a century and that more than 20 yr have passed since the cloning of the GC …
over half a century and that more than 20 yr have passed since the cloning of the GC …
[PDF][PDF] Novel glucocorticoids: where are we now and where do we want to go
F Buttgereit, CM Spies, JW Bijlsma - Clin Exp Rheumatol, 2015 - clinexprheumatol.org
Glucocorticoid (GC) therapy is widely accepted as effective treatment for many inflammatory
conditions. However, the potential of GC to produce adverse effects may prompt both …
conditions. However, the potential of GC to produce adverse effects may prompt both …
Unraveling the functions of the membrane‐bound glucocorticoid receptors: first clues on origin and functional activity
C Strehl, F Buttgereit - Annals of the New York Academy of …, 2014 - Wiley Online Library
Glucocorticoids (GCs) are routinely used to treat a wide range of rheumatic and other
inflammatory diseases. GCs are steroidal drugs that exert their strong anti‐inflammatory and …
inflammatory diseases. GCs are steroidal drugs that exert their strong anti‐inflammatory and …
The search for safer glucocorticoid receptor ligands
J Rosen, JN Miner - Endocrine reviews, 2005 - academic.oup.com
Steroidal glucocorticoids are commonly used due to their powerful antiinflammatory activity.
However, despite their excellent efficacy, severe side effects frequently limit the use of these …
However, despite their excellent efficacy, severe side effects frequently limit the use of these …
Defining the role of glucocorticoids in inflammation
S Ronchetti, G Migliorati, S Bruscoli… - Clinical Science, 2018 - portlandpress.com
An established body of knowledge and clinical practice has argued in favor of the use of
glucocorticoids in various chronic inflammatory and autoimmune diseases. However, the …
glucocorticoids in various chronic inflammatory and autoimmune diseases. However, the …