Inactivation of the Monofunctional Peptidoglycan Glycosyltransferase SgtB Allows Staphylococcus aureus To Survive in the Absence of Lipoteichoic Acid

E Karinou, CF Schuster, M Pazos, W Vollmer… - Journal of …, 2019 - Am Soc Microbiol
The cell wall of Staphylococcus aureus is composed of peptidoglycan and the anionic
polymers lipoteichoic acid (LTA) and wall teichoic acid. LTA is required for growth and …

Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids

S Brown, G Xia, LG Luhachack… - Proceedings of the …, 2012 - National Acad Sciences
Staphylococcus aureus peptidoglycan (PG) is densely functionalized with anionic polymers
called wall teichoic acids (WTAs). These polymers contain three tailoring modifications: d …

The length of lipoteichoic acid polymers controls Staphylococcus aureus cell size and envelope integrity

AR Hesser, LM Matano, CR Vickery… - Journal of …, 2020 - Am Soc Microbiol
The opportunistic pathogen Staphylococcus aureus is protected by a cell envelope that is
crucial for viability. In addition to peptidoglycan, lipoteichoic acid (LTA) is an especially …

A Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content: LTA governs bacterial surface properties and autolysin activity

I Fedtke, D Mader, T Kohler, H Moll… - Molecular …, 2007 - Wiley Online Library
Many Gram‐positive bacteria produce lipoteichoic acid (LTA) polymers whose physiological
roles have remained a matter of debate because of the lack of LTA‐deficient mutants. The …

Salt-induced stress stimulates a lipoteichoic acid-specific three-component glycosylation system in Staphylococcus aureus

K Kho, TC Meredith - Journal of bacteriology, 2018 - Am Soc Microbiol
Lipoteichoic acid (LTA) in Staphylococcus aureus is a poly-glycerophosphate polymer
anchored to the outer surface of the cell membrane. LTA has numerous roles in cell …

Genes Required for Glycolipid Synthesis and Lipoteichoic Acid Anchoring in Staphylococcus aureus

A Gründling, O Schneewind - Journal of bacteriology, 2007 - Am Soc Microbiol
Staphylococcus aureus lipoteichoic acid (LTA) is composed of a linear 1, 3-linked
polyglycerolphosphate chain and is tethered to the bacterial membrane by a glycolipid …

Pathways and roles of wall teichoic acid glycosylation in Staphylococcus aureus

V Winstel, G Xia, A Peschel - International Journal of Medical Microbiology, 2014 - Elsevier
The thick peptidoglycan layers of Gram-positive bacteria are connected to polyanionic
glycopolymers called wall teichoic acids (WTA). Pathogens such as Staphylococcus aureus …

c-di-AMP Is a New Second Messenger in Staphylococcus aureus with a Role in Controlling Cell Size and Envelope Stress

RM Corrigan, JC Abbott, H Burhenne, V Kaever… - PLoS …, 2011 - journals.plos.org
The cell wall is a vital and multi-functional part of bacterial cells. For Staphylococcus aureus,
an important human bacterial pathogen, surface proteins and cell wall polymers are …

Pleiotropic Roles of Polyglycerolphosphate Synthase of Lipoteichoic Acid in Growth of Staphylococcus aureus Cells

Y Oku, K Kurokawa, M Matsuo, S Yamada… - Journal of …, 2009 - Am Soc Microbiol
Lipoteichoic acid (LTA) is one of two anionic polymers on the surface of the gram-positive
bacterium Staphylococcus aureus. LTA is critical for the bacterium-host cell interaction and …

Cross-Linked Peptidoglycan Mediates Lysostaphin Binding to the Cell Wall Envelope of Staphylococcus aureus

A Gründling, O Schneewind - Journal of bacteriology, 2006 - Am Soc Microbiol
Staphylococcus simulans bv. staphylolyticus secretes lysostaphin, a bacteriocin that cleaves
pentaglycine cross bridges in the cell wall of Staphylococcus aureus. The C-terminal cell …