Carbon monoxide (CO) is a pollutant commonly recognized for its toxicological attributes,
including CNS and cardiovascular effects. But CO is also formed endogenously in …

Carbon monoxide (CO) is an odorless, colorless and non-irritating gas. Even a small amount
of CO exposure is possibly associated with specific toxic effects. CO is also produced …

Carbon monoxide (CO) is produced endogenously through the oxidative catabolism of
heme by heme oxygenase (HO). First described as a putative neuronal signaling …

Less than 10 years have elapsed since the possibility of carbon monoxide (CO) being a
novel signaling agent was first discussed. 1 In this time, a wealth of data has accrued …

Arterial vessels express one or more heme oxygenase (HO) isoenzymes that catalyze the
metabolism of heme to carbon monoxide (CO) and biliverdin. Carbon monoxide promotes …

Carbon monoxide (CO) is an endogenously generated gas that may play an important
physiological role in the circulation. CO is generated by vascular cells as a byproduct of …

Carbon monoxide is a molecule with notoriety in modern culture and extensive
documentation regarding its toxic physiological effects, long predating its formal discovery in …

Rationale: Vascular tissues produce carbon monoxide (CO) via HO-dependent and HO-
independent mechanisms; the former in tandem with biliverdin and iron and the latter as a …

Carbon monoxide (CO) is an endogenously derived gas formed from the breakdown of
heme by the enzyme heme oxygenase. Although long considered an insignificant and …

Over the last decade, studies have unraveled many aspects of endogenous production and
physiological functions of carbon monoxide (CO). The majority of endogenous CO is …