Objectives: To investigate the disruption of neural circuits in the frontal lobes and limbic
structures in late-life depressed patients compared with healthy controls, and to examine the …

Objective: To evaluate the location and the degree of white matter damage in late-life
depression using diffusion tensor imaging (DTI). Methods: Thirty-one patients with late-life …

OBJECTIVE: The purpose of this study was to determine whether microstructural
abnormalities in the white matter of the dorsolateral prefrontal cortex are associated with late …

Previous studies have demonstrated lower-diffusion anisotropy within white matter in late-
onset depression measured by diffusion tensor imaging, which provides information about …

BACKGROUND: The dorsolateral prefrontal cortex (DLPFC) and anterior cingulate cortex
(ACC) are critical for mood regulation. Alterations in the white matter connections of these …

BACKGROUND: Numerous studies have revealed white matter abnormalities in late-life
depression (LLD). The objective was to investigate the integrity of white matter tracts in …

Objective: The aim of this study was to explore the microstructural integrity of whole-brain
white matter by diffusion tensor imaging in first-episode, treatment-naive young adults with …

Prefrontal impairments have been hypothesized to be most strongly associated with the
cognitive and emotional dysfunction in depression. Recently, white matter microstructural …

This study was conducted to elucidate the effects of electroconvulsive therapy (ECT) on
frontal white matter in late-life depressed patients. Diffusion tensor imaging was performed …

Objective: The purpose of our study was to investigate alterations of white matter integrity in
adults with major depressive disorder (MDD) using magnetic resonance imaging (MRI) …