Smoking is considered an important risk factor for bladder cancer (BC), yet molecular
characterization of BC in nonsmokers has not been extensively studied. Here, we compare …

Background: Infiltrating urothelial carcinoma (UC) is the most common variant of urinary
bladder cancer. The prognosis for muscle infiltrating or metastatic UC of the bladder is poor …

Background Bladder cancer is the fifth most common cancer in the United States and
smoking is the largest known risk factor. Tobacco-derived carcinogens may induce the …

Background Fifty percent of patients with muscle–invasive bladder cancer (MI-BC) die from
their disease and current chemotherapy treatment only marginally increases survival. Novel …

Smoking status has been associated with both an increased risk of developing bladder
cancer and worse prognosis, but its impact on the risk of nonmuscleinvasive bladder cancer …

BACKGROUND: Traditional single‐marker and multimarker molecular profiling approaches
in bladder cancer do not account for major risk factors and their influence on clinical …

Objective To explore the relation between cigarette smoking intensity and bladder cancer
aggressiveness at first diagnosis. Methods Patients diagnosed with urinary bladder cancer …

554 Background: Cigarette smoking is a known risk factor for bladder cancer. Smokers have
been reported to have greater ERCC2-Signature mutations and APOBEC-Signature 13 …

Objective Epidemiologic studies have linked smoking to various malignancies, including
bladder cancer, but its underlying biological functions remain elusive. Currently, we aimed to …

399 Background: Adenocarcinoma (ADA) and squamous cell carcinoma (SCC) are rare,
aggressive subtypes of bladder cancer, for which no clear standard of care exists. We report …