[HTML][HTML] Extracellular vesicles in amyotrophic lateral sclerosis

G McCluskey, KE Morrison, C Donaghy, F Rene… - Life, 2022 - mdpi.com
Amyotrophic Lateral Sclerosis is a progressive neurodegenerative disease and is the most
common adult motor neuron disease. The disease pathogenesis is complex with the …

[HTML][HTML] Recent advances in extracellular vesicles in amyotrophic lateral sclerosis and emergent perspectives

GJM Afonso, C Cavaleiro, J Valero, SI Mota, E Ferreiro - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a severe and incurable neurodegenerative disease
characterized by the progressive death of motor neurons, leading to paralysis and death. It is …

[HTML][HTML] Role of extracellular vesicles in amyotrophic lateral sclerosis

D Ferrara, L Pasetto, V Bonetto, M Basso - Frontiers in neuroscience, 2018 - frontiersin.org
Amyotrophic Lateral Sclerosis (ALS) is the most common motor neuron disease in adults
and primarily targets upper and lower motor neurons. The progression of the disease is …

[HTML][HTML] Pathological proteins are transported by extracellular vesicles of sporadic amyotrophic lateral sclerosis patients

D Sproviero, S La Salvia, M Giannini… - Frontiers in …, 2018 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a progressive adult-onset neurodegenerative disease,
that affects cortical, bulbar and spinal motor neurons, and it is considered a proteinopathy, in …

[HTML][HTML] Pathogenic extracellular vesicle (EV) signaling in amyotrophic lateral sclerosis (ALS)

G Kim, X Chen, Y Yang - Neurotherapeutics, 2022 - Elsevier
Extracellular vesicles (EVs), once considered a pathway for cells to remove waste, have now
emerged as an important mechanism for intercellular communication. EVs are particularly …

[HTML][HTML] Extracellular vesicles and amyotrophic lateral sclerosis: from misfolded protein vehicles to promising clinical biomarkers

D Gagliardi, N Bresolin, GP Comi, S Corti - Cellular and Molecular Life …, 2021 - Springer
Extracellular vesicles (EVs) are small reservoirs of different molecules and important
mediators of cell-to-cell communication. As putative vehicles of misfolded protein …

[HTML][HTML] Therapeutic and diagnostic potential of extracellular vesicles in amyotrophic lateral sclerosis

TJ Ellison, SL Stice, Y Yao - Extracellular Vesicle, 2023 - Elsevier
As a late-onset and fatal neurodegenerative disease that affects upper and lower motor
neurons, amyotrophic lateral sclerosis (ALS) is a difficult disease to diagnose and treat …

[HTML][HTML] Extracellular vesicles as innovative treatment strategy for amyotrophic lateral sclerosis

K Wang, Y Li, C Ren, Y Wang, W He… - Frontiers in Cell and …, 2021 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron degenerative
disease, and it is hard to diagnose in the early stage, and treatment means are limited, and …

Extracellular vesicles and their diagnostic potential in amyotrophic lateral sclerosis

J Roy, D Saucier, C O'Connell - Clinica Chimica Acta, 2019 - Elsevier
Extracellular vesicles, small reservoirs that carry various biomolecules, have gained
significant interest from the clinical field in recent years based on the diagnostic, therapeutic …

[HTML][HTML] Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis

L Pasetto, S Callegaro, A Corbelli, F Fiordaliso… - Molecular …, 2021 - Springer
Background Amyotrophic lateral sclerosis (ALS) is a multifactorial, multisystem motor neuron
disease for which currently there is no effective treatment. There is an urgent need to identify …