Clathrin-mediated endocytosis (CME) internalizes plasma membrane by reshaping small
regions of the cell surface into spherical vesicles. The key mechanistic question of how coat …

In endocytosis, scaffolding is one of the mechanisms to create membrane curvature by
moulding the membrane into the spherical shape of the clathrin cage. However, the impact …

Eukaryotic cells use clathrin-mediated endocytosis to take up a large range of extracellular
cargo. During endocytosis, a clathrin coat forms on the plasma membrane, but it remains …

Cellular activity depends to a large extent on membrane bilayer dynamics. Many processes,
such as organelle biogenesis and vesicular transport, rely on alterations in membrane …

During clathrin-mediated endocytosis (CME), flat plasma membrane is remodeled to
produce nanometer-scale vesicles. The mechanisms underlying this remodeling are not …

Clathrin polymerization and changes in plasma membrane architecture are necessary steps
in forming vesicles to internalize cargo during clathrin-mediated endocytosis (CME) …

Clathrin-mediated endocytosis is an essential cellular mechanism by which all eukaryotic
cells regulate their plasma membrane composition to control processes ranging from cell …

Clathrin-mediated endocytosis (CME) involves nanoscale bending and inward budding of
the plasma membrane, by which cells regulate both the distribution of membrane proteins …

Dynamics of endocytic clathrin-coated structures can be remarkably divergent across
different cell types, cells within the same culture, or even distinct surfaces of the same cell …

Budding of membranes by protein coats is a universal phenomenon that is critically
important in cellular trafficking pathways. Recent experiments have demonstrated that …