As vertebrates evolved from protochordates, they shifted to a more predatory lifestyle, and
radiated and adapted to most niches of the planet. This process was largely facilitated by the …

The neural crest is a vertebrate-specific migratory stem cell population that generates a
remarkably diverse set of cell types and structures. Because many of the morphological …

Vertebrates possess lineage-specific characteristics. These include paired anterior sense
organs and a robust, modular head skeleton built of cellular cartilage and bone. All of these …

The neural crest is a vertebrate-specific embryonic stem cell population that gives rise to a
vast array of cell types throughout the animal body plan. These cells are first born at the …

In the vertebrate embryo, the neurectodermal neural crest cells (NCC) have remarkably
broad potencies, giving rise, after a migratory phase, to neurons and glial cells in the …

In the vertebrate embryo, multiple cell types originate from a common structure, the neural
crest (NC), which forms at the dorsal tips of the neural epithelium. The NC gives rise to …

Highlights•Genetic tools allow single cell lineage-tracing at high resolution.•Single cell
lineage-tracing demonstrates multipotency of neural crest cells.•Genetic lineage tracing …

The neural crest is an embryonic cell population that gives rise to an array of tissues and
structures in adult vertebrates including most of the head skeleton. Because neural crest …

The emergence of multipotent and migratory neural crest (NC) cells defines a key
evolutionary transition from invertebrates to vertebrates. Studies in vertebrates have …

In their seminal 1983 paper, Gans and Northcutt proposed that evolution of the vertebrate
'new head'was made possible by the advent of the neural crest and cranial placodes. The …