No Heading Purpose. To investigate the pharmacokinetics, long-term tissue retention of Gd
(III) ions, and magnetic resonance imaging (MRI) contrast enhancement of extracellular …

Purpose The aim of this study was to evaluate stability and Gd tissue distribution of a
biodegradable macromolecular MRI contrast agent, GDCC. Methods Kinetic stability of …

Purpose The purpose of this study was to synthesize biodegradable Gd-DTPA l-cystine
bisamide copolymers (GCAC) as safe and effective, macromolecular contrast agents for …

The purpose of this study was to investigate the effect of PEGylation of novel biodegradable
macromolecular polydisulfide Gd (III) complexes, gadolinium …

Purpose To investigate plasma pharmacokinetics and biodistribution of biodegradable
polydisulfide Gd (III) complexes, Gd-DTPA cystine copolymers (GDCP) and Gd-DTPA …

Macromolecular Gd (III) chelates are superior magnetic resonance imaging (MRI) contrast
agents for blood pool and tumor imaging. However, their clinical development is limited by …

Although polymeric magnetic resonance imaging (MRI) agents have significantly improved
relaxivity and prolonged circulation time in vivo compared with current imaging agents, the …

The purpose of this study was to evaluate poly (l‐glutamic acid)‐benzyl‐DTPA–Gd (PG–Gd),
a new biodegradable macromolecular magnetic resonance imaging contrast agent, for its …

The structures of polydisulfide‐based biodegradable macromolecular Gd (III) complexes
were modified to improve their in vivo retention time and MRI contrast enhancement. Steric …

Biodegradable macromolecular Gd (III) complexes, Gd-DTPA cystine copolymers (GDCP),
were grafted with PEG of different sizes to modify the physicochemical properties and in vivo …