It is generally accepted that the β2‐integrin is restricted to mononuclear leukocytes. The
objective of this study was to determine whether neutrophils can also express β1‐integrin …

Although the importance of β1 integrin‐mediated binding to adhesion molecules and
extracellular matrix (ECM) molecules is well established for most types of leukocytes, the …

Induction of β1 integrin (CD49/CD29) expression in polymorphonuclear leukocytes (PMN)
has been shown to be associated with transendothelial migration recently. Yet, β1 integrin …

In this study we investigated the possibility that an alternative pathway exists for neutrophil
recruitment, namely an α4β1-dependent pathway. A parallel plate chamber was used to …

Chemoattractants differ in their capacity to stimulate neutrophils to adhere to and to migrate
through matrices containing fibrin. Formyl methionyl leucyl phenylalanine (fMLP) stimulates …

In general, neutrophils are assumed not to express the α 4-integrin, a molecule implicated in
the recruitment of mononuclear leukocytes and eosinophils to sites of inflammation. In this …

Flow cytometry and fluorescently labeled monoclonal antibodies were used to investigate
endocytosis of human neutrophil ß2 integrins following cellular activation. GDI 8 initially …

The aggregation of human neutrophils in suspension has features that are analogous to
their attachment to activated endothelium in that both involve selectin and β2-integrin …

Accumulation of leukocytes in inflamed tissue involves their migration through vascular
endothelium and then in the connective tissue. Recently we utilized a barrier of human …

Regulated adhesion of leukocytes to the extracellular matrix is essential for transmigration of
blood vessels and subsequent migration into the stroma of inflamed tissues. Although β 2 …