The cellular and molecular mechanisms responsible for the initiation and progression of
osteoarthritis (OA), and in particular cartilage degeneration in OA, are not completely …

Osteoarthritis (OA), one of the most common skeletal disorders characterized by cartilage
degradation and osteophyte formation in joints, is induced by accumulated mechanical …

Much of the attention in developing diagnostic tools and therapeutic interventions for the
management of osteoarthritis (OA) has focused on the preservation or repair of articular …

Today, the most frequent chronic musculoskeletal disorder and the leading cause of
disability in the elderly is osteoarthritis (OA). Approximately 43 million people in the United …

When considering the pathogenesis of osteoarthritis (OA), it is important to review the
contribution of bone in addition to the contribution of cartilage and synovium. Although bone …

Once believed to be limited to articular cartilage, osteoarthritis is now considered to be an
organ disease of the “whole joint.” Damage to the articular surface can lead to, be caused …

Osteoarthritis (OA) is the most common form of arthritis. It has been regarded as a disease of
articular cartilage, with evidence of articular cartilage degeneration followed by erosion, the …

Osteoarthritis has developed into the most common chronic disease in the highly
industrialized nations. Moreover, because of the prevalence of the disease in the elderly …

Osteoarthritis (OA) is a debilitating, progressive disease of diarthrodial joints associated with
aging. At the molecular level, OA is characterized by an imbalance between anabolic (ie …

Osteoarthritis (OA) is the most common form of arthritis and a major cause of pain and
disability in older adults (1). Often OA is referred to as degenerative joint disease “(DJD)” …