The rising prevalence of osteoarthritis (OA) in the general population has necessitated the
development of novel treatment options. It is critical to recognize the joint as a separate …

Osteoarthritis (OA) is the most common form of arthritic disease, and it is a major cause of
disability and impaired quality of life in the elderly. A hallmark of the disease is progressive …

Osteoarthritis represents the most frequently diagnosed condition of the musculoskeletal
system and accounts for a high amount of direct and indirect socioeconomic costs …

Structural disturbances of the subchondral bone are a hallmark of osteoarthritis (OA),
including sclerotic changes, cystic lesions, and osteophyte formation. Osteocytes act as …

Osteoarthritis (OA) can affect every joint, especially the knee. Given the complexity of this
pathology, OA is difficult to treat with current therapies, which only relieve pain and …

Osteoarthritis (OA) is a long-term condition that causes joint pain and reduced movement.
Notably, the same pathways governing cell growth, death, and differentiation during the …

In osteoarthritis (OA), adult articular chondrocytes undergo phenotypic modulation in
response to alterations in the environment owing to mechanical injury and inflammation …

Articular chondrocytes maintain cartilage matrix turnover and have the capacity for anabolic
and catabolic activities that can be influenced by injury and disease. This study tested the …

Osteoarthritis (OA) is a disease of high ethical and economical importance. In advanced
stages, the patients suffer from severe pain and restriction of mobility. The consequence in …

Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the
adult population. OA is primarily caused by trauma induced by an external force or by age …