Multiple Sclerosis is a chronic neuro-immune disorder of the central CNS. MS belongs to the
large group of multifactorial and multi-genic disease. The TNFα gene encodes pro …

Tumor necrosis factor-alpha TNF-α) is a pro-inflammatory cytokine that is involved in the
pathogenesis of Multiple Sclerosis. The current study was designed to examine the …

Dysregulation in the expression of pro‐and anti‐inflammatory cytokines is one of the
milestones in multiple sclerosis (MS) development and progression. Tumour necrosis factor …

The association between multiple sclerosis (MS) and tumor necrosis factor-alpha gene (TNF-
α) polymorphisms has been analyzed in several studies, but conflicting results have been …

Background: TNF-α has a dual role in multiple sclerosis (MS), contributing to both protective
and harmful effects. It activates immune cells, promotes the formation of inflammatory lesions …

Tumor necrosis factor (TNF) α has been considered the prototypic cytopathogenic cytokine
in multiple sclerosis (MS), but recently this cytokine has been shown to possess significant …

Background: Multiple sclerosis (MS) is an immune-mediated disease of polygenic etiology.
Tumor necrosis factor-α (TNF-α) microsatellite as a proinflammatory cytokine is believed to …

Background: Environmental and genetic factors are thought to be involved in the
pathogenesis of multiple sclerosis (MS). Polymorphisms of tumor necrosis factor (TNF)-α …

Objective–To investigate the association between tumor necrosis factor‐α (TNF‐α) G‐308A,
tumor necrosis factor‐β (TNF‐β) G+ 252A and interleukin‐4 (IL‐4) C‐590T polymorphisms …

Multiple sclerosis (MS) is a complex polygenic disease in which gene-environment
interactions are important. A number of studies have investigated the association between …