Aims Anti-allergic effects and action mechanism of phloretin (Phl) and biochanin A (BioA) on
the IgE–antigen complex-mediated allergic responses in rat basophilic leukemia RBL-2H3 …

The anti-allergic effect of berberine was evaluated in cellular and animal models of allergic
responses. In this study, the results of the in vitro model of immunoglobulin (Ig) E-mediated …

Background Currently, there is no satisfactory treatment for IgE-mediated food allergy. Food
Allergy Herbal Formula 2 (FAHF-2) and butanol-purified FAHF-2 (B-FAHF-2) have been …

Kaempferol is one of the most commonly found dietary flavonoids. The exposure to
kaempferol is known to inhibit degranulation from mast cells, but the inhibitory mechanism of …

Mast cells are effector cells that initiate allergic inflammatory immune responses by inducing
inflammatory mediators. Boehmeria nivea (Linn.) Gaudich is a natural herb in the nettle …

Mast cells play an essential role in IgE‐FcεR1‐mediated allergic diseases. Citrus aurantium
is a prolific source of flavonoids with various biological activities, including anti …

We isolated the 4 kinds of flavonoids from strawberry 'Nohime'and examined the effect of
these flavonoids on the degranulation in RBL-2H3 cells. The flavonoids were found to …

AIM: To investigate the effects of shikonin on phorbol myristate acetate (PMA) plus cyclic
adenosine monophosphate (cAMP)-induced T helper (TH) 2 cell cytokine production, and …

The incidence of allergic diseases has increased to such a point that they have become
common and have reached epidemic levels. However, their pathogenesis is not fully …

Roxatidine is an active metabolite of roxatidine acetate hydrochloride which is a histamine
H2-receptor antagonist that is used to treat gastric and duodenal ulcers. In this study, we …