To study the folding/unfolding properties of a β-amyloid peptide Aβ12–36 of Alzheimer's
disease, five molecular dynamics simulations of Aβ12–36 in explicit water were done at 450 …

The amyloid β-peptides (Aβs), containing 39–43 residues, are the key protein components
of amyloid deposits in Alzheimer's disease. To structurally characterize the dynamic …

Amyloid β-peptide (Aβ) is the major component of plaques found in the brains of Alzheimer's
patients. Among its two predominate forms− Aβ (1–40) and Aβ (1–42), the latter possesses …

Structural properties of Aβ (16–35) fragment are investigated as a model for the amyloid-β
peptide excluding its coil-inducing terminals. Our replica-exchange molecular dynamics …

The conformational states sampled by the Alzheimer amyloid β (10-35)(Aβ 10-35) peptide
were probed using replica-exchange molecular dynamics (REMD) simulations in explicit …

To study the early stage of amyloid‐β peptide (Aβ) aggregation, hexamers of the wild‐type
(WT) Aβ16–35 and its mutants with amyloid‐like conformations have been studied by …

Aβ (1− 40) and Aβ (1− 42) are the main forms of amyloid β (Aβ) peptides in the brain of
Alzheimer's patients; however, the latter possesses much stronger aggregation and …

Aβ (1–40) and Aβ (1–42) are the two predominant forms of amyloid β-peptide (Aβ) in the
plaques found in the brains of Alzheimer's patients. They possess identical amino acid …

The monomeric Alzheimer's β amyloid peptide, Aβ, is known to adopt a disordered state in
water at room temperature, and a circular dichroism (CD) spectroscopy experiment has …

The molecular mechanism of the conformational transition of amyloid peptide 42 (Aβ42)
inhibited by trehalose was studied using molecular dynamics simulation. It is confirmed that …