Leptin is a peptide hormone that has been characterized as the ligand of leptin receptor
(LEPR). The observation of leptin secretion and leptin receptor expression beyond the …

Leptin is an obesity-associated adipokine that is known to regulate energy metabolism and
reproduction and to control appetite via the leptin receptor. Recent work has identified …

Obesity is a global pandemic characterized by high levels of body fat (adiposity) and derived-
cytokines (ie., leptin). Research shows that adiposity and leptin provide insight on the link …

Leptin acts as an adipocytokine functions via the leptin receptor, which stimulates growth,
migration, and invasion of cancer cells. This study is aimed at identifying leptin as a …

High plasma levels of leptin, a major adipocytokine produced by adipocytes, are correlated
with increased fat mass in obese state. Leptin is emerging as a key candidate molecule …

Leptin is an important regulator of basal metabolism and food intake, with a pivotal role in
obesity. Leptin exerts many different actions on various tissues and systems, including …

Obesity, defined as the abnormal or excessive expansion of white adipose tissue, has
reached pandemic proportions and is recognized as an important health concern since it is …

Leptin, a product of Ob gene from adipocytes regulates appetite, energy expenditure and
body mass composition by decreasing orexigenic and increasing anorexigenic …

Background Circulating leptin can directly act on tumor cells. However, a recent meta-
analysis showed that plasma leptin concentration had no significant effect on the survival of …

Leptin is a hormone produced and secreted by adipose tissue. It is a member of adipokine
family with a principal role in body weight regulation. It is reported that low brain leptin levels …