Unprecedented DNA Photocleavage Mediated by Quinolinium Pentamethine Carbocyanine Dyes in the NIR Wavelength Range

EO Ahoulou - 2021 - scholarworks.gsu.edu
Here we report the DNA photocleavage abilities of near-infrared (NIR) quinolinium
pentamethine carbocyanine dyes substituted with either bromine, chlorine, or hydrogen at …

[HTML][HTML] DNA photocleavage in the near-infrared wavelength range by 2-quinolinium dicarbocyanine dyes

EO Ahoulou, KK Drinkard, K Basnet, A St. Lorenz… - Molecules, 2020 - mdpi.com
Here, we report the syntheses of two pentamethine cyanine dyes containing quinolinium
rings and substituted with either hydrogen (3) or bromine (4) at the meso carbon. The …

DNA Photo-cleavage and Interactions by Quinoline Cyanine Dyes; Towards Improving Photodynamic Cancer Therapy

T Fatemipouya - 2016 - scholarworks.gsu.edu
Photodynamic therapy (PDT) is a cancer treatment method in which a photosensitizer, light
of a particular wavelength, and also oxygen are used to destroy cancerous cells. Cancer …

Oxidative cleavage of DNA by pentamethine carbocyanine dyes irradiated with long-wavelength visible light

CT Mapp, EA Owens, M Henary, KB Grant - Bioorganic & Medicinal …, 2014 - Elsevier
Here we report the synthesis of seven symmetrical carbocyanine dyes in which two nitrogen-
substituted benz [e] indolium rings are joined by a pentamethine bridge that is meso …

Single photon DNA photocleavage at 830 nm by quinoline dicarbocyanine dyes

K Basnet, T Fatemipouya, AS Lorenz… - Chemical …, 2019 - pubs.rsc.org
We have synthesized symmetrical carbocyanine dyes in which two 4-quinolinium rings are
joined by a pentamethine bridge that is meso-substituted with H or Cl. Irradiation of the …

Synthesis, Characterization, Optical Properties and DNA Cleavage Study of Symmetrical Pentamethine Cyanine Dyes Containing Quinoline Moieties

K Ilina - 2020 - scholarworks.gsu.edu
This thesis outlines a review of the history, synthetic procedures, optical properties, and
applications of quinoline-containing cyanine dyes in the first chapter. The second chapter …

Investigation into Novel Mitochondrial Targeting Cyanine Dyes as Potential Photosensitizing Agents for Photodynamic Therapy

D Brewer - 2022 - scholarworks.gsu.edu
Carbocyanine dyes are a class of organic compounds with high conjugation that enable
them to act as photosensitizing agents in photodynamic therapy (PDT). These compounds …

Near-infrared-emitting hemicyanines and their photodynamic killing of cancer cells

M Santra, M Owens, G Birch… - ACS Applied Bio …, 2021 - ACS Publications
A series of hemicyanine dyes was synthesized starting from the vinyl chloride-based
cyanine dye IR-780. The dyes absorbed and emitted in the near-infrared region, while heavy …

Dye-Sensitized DNA Photocleavage Facilitated by Donor-Acceptor Fluorophores in the NIR Wavelength Range

C Seudieu - 2022 - scholarworks.gsu.edu
We report the DNA photocleavage abilities of GEO30 and GEO31, near-infrared (NIR) donor-
π-acceptor fluorophores (D-π-A) with a chloroacrylic acid acceptor linked to an indole donor …

Design and synthesis of symmetrical pentamethine cyanine dyes as NIR photosensitizers for PDT

B Ciubini, S Visentin, L Serpe, R Canaparo, A Fin… - Dyes and …, 2019 - Elsevier
Herein, we report the synthesis and spectroscopic characterization of novel Near Infra-Red
(NIR) pentamethine cyanine dyes, as potential photosensitizers for Photodynamic Therapy …