Single cell scale neuronal and glial gene expression and putative cell phenotypes and networks in the nucleus tractus solitarius in an alcohol withdrawal time series
SJ O'Sullivan, D McIntosh-Clarke, J Park… - Frontiers in Systems …, 2021 - frontiersin.org
Alcohol withdrawal syndrome (AWS) is characterized by neuronal hyperexcitability,
autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) …
autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) …
[PDF][PDF] Single neuronal and glial gene expression in the nucleus tractus solitarius in an alcohol withdrawal time series reveals novel cellular phenotypes and networks
SJ O'Sullivan, D McIntosh-Clarke, J Park, R Vadigepalli… - 2021 - pdfs.semanticscholar.org
Alcohol withdrawal syndrome (AWS) is characterized by neuronal hyperexcitability,
autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) …
autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) …
Transcriptome changes in the nucleus of the solitary tract induced by repeated stress, alcohol dependence, or stress-induced drinking in dependent mice
Stress increases alcohol consumption in dependent animals and contributes to the
development of alcohol use disorder. The nucleus of the solitary tract (NTS) is a critical …
development of alcohol use disorder. The nucleus of the solitary tract (NTS) is a critical …
Glial gene networks associated with alcohol dependence
Chronic alcohol abuse alters the molecular structure and function of brain cells. Recent work
suggests adaptations made by glial cells, such as astrocytes and microglia, regulate …
suggests adaptations made by glial cells, such as astrocytes and microglia, regulate …
Chronic alcohol exposure alters transcription broadly in a key integrative brain nucleus for homeostasis: the nucleus tractus solitarius
MY Covarrubias, RL Khan… - Physiological …, 2006 - journals.physiology.org
Chronic exposure to alcohol modifies physiological processes in the brain, and the severe
symptoms resulting from sudden removal of alcohol from the diet indicate that these …
symptoms resulting from sudden removal of alcohol from the diet indicate that these …
A single-nucleus transcriptomics study of alcohol use disorder in the nucleus accumbens
EJCG van den Oord, LY Xie, M Zhao, KA Aberg… - medRxiv, 2022 - medrxiv.org
Alcohol use disorder (AUD) is a significant public health problem. Gene expression studies
offer promising opportunities to better understand the underlying pathogenic processes. As …
offer promising opportunities to better understand the underlying pathogenic processes. As …
[HTML][HTML] Single-cell profiling of glial cells from the mouse amygdala under opioid dependent and withdrawal states
The cycle of substance use disorder (SUD) leading to dependence is a complex process
involving multiple neurocircuitries and brain regions. The amygdala is the core brain region …
involving multiple neurocircuitries and brain regions. The amygdala is the core brain region …
Bulk and Single-cell Transcriptomic Brain Data Identify Overlapping Processes and Cell-types with Human AUD and Mammalian Models of Alcohol Use
This study explores the neurobiological underpinnings of alcohol use disorder (AUD) by
integrating bulk and single-cell transcriptomic data from humans, primates, and mice across …
integrating bulk and single-cell transcriptomic data from humans, primates, and mice across …
The role of alcohol in modifying behavior
J Peters, L Trabace, G Di Giovanni - Frontiers in Behavioral …, 2023 - frontiersin.org
This special topic presents experimental work on the effects of alcohol (ethanol) on the
brain, and how these effects impact behavior across multiple domains. The World Health …
brain, and how these effects impact behavior across multiple domains. The World Health …
The synaptoneurosome transcriptome: a model for profiling the emolecular effects of alcohol
D Most, L Ferguson, Y Blednov, RD Mayfield… - The …, 2015 - nature.com
Chronic alcohol consumption changes gene expression, likely causing persistent
remodeling of synaptic structures via altered translation of mRNAs within synaptic …
remodeling of synaptic structures via altered translation of mRNAs within synaptic …
相关搜索
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