Alcohol withdrawal syndrome (AWS) is characterized by neuronal hyperexcitability,
autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) …

Alcohol withdrawal syndrome (AWS) is characterized by neuronal hyperexcitability,
autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) …

Stress increases alcohol consumption in dependent animals and contributes to the
development of alcohol use disorder. The nucleus of the solitary tract (NTS) is a critical …

Chronic alcohol abuse alters the molecular structure and function of brain cells. Recent work
suggests adaptations made by glial cells, such as astrocytes and microglia, regulate …

Chronic exposure to alcohol modifies physiological processes in the brain, and the severe
symptoms resulting from sudden removal of alcohol from the diet indicate that these …

Alcohol use disorder (AUD) is a significant public health problem. Gene expression studies
offer promising opportunities to better understand the underlying pathogenic processes. As …

The cycle of substance use disorder (SUD) leading to dependence is a complex process
involving multiple neurocircuitries and brain regions. The amygdala is the core brain region …

This study explores the neurobiological underpinnings of alcohol use disorder (AUD) by
integrating bulk and single-cell transcriptomic data from humans, primates, and mice across …

This special topic presents experimental work on the effects of alcohol (ethanol) on the
brain, and how these effects impact behavior across multiple domains. The World Health …

Chronic alcohol consumption changes gene expression, likely causing persistent
remodeling of synaptic structures via altered translation of mRNAs within synaptic …