Direct oral anticoagulants: current indications and unmet needs in the treatment of venous thromboembolism

L Bertoletti, E Ollier, C Duvillard, X Delavenne… - Pharmacological …, 2017 - Elsevier
The treatment of acute venous thromboembolism (VTE) is being completely modified with
the development of direct oral anticoagulants (DOACs). Rivaroxaban, apixaban and …

Management of venous thromboembolism: recent advances in oral anticoagulation therapy

SW Finks, TC Trujillo… - Annals of …, 2016 - journals.sagepub.com
Objective: To review clinical data on direct oral anticoagulants (DOACs) used in the acute
treatment of venous thromboembolism (VTE) as well as practical considerations when using …

Safety of direct oral anticoagulants versus traditional anticoagulants in venous thromboembolism

M Giustozzi, L Franco, MC Vedovati, C Becattini… - Journal of thrombosis …, 2019 - Springer
Venous thromboembolism (VTE) is a leading cause of morbidity and mortality worldwide.
For decades, low molecular weight heparins (LMWH) and vitamin K-antagonists have been …

Direct‐acting oral anticoagulants: pharmacology, indications, management, and future perspectives

A Gómez‐Outes, ML Suárez‐Gea… - European journal of …, 2015 - Wiley Online Library
In recent years, several direct‐acting oral anticoagulants (DOAC) have become available for
use in Europe and other regions in indications related to prophylaxis and treatment of …

Direct oral anticoagulants and the paradigm shift in the management of venous thromboembolism

HY Lim, H Nandurkar, P Ho - Seminars in thrombosis and …, 2018 - thieme-connect.com
The advent of direct oral anticoagulants (DOACs) has revolutionized anticoagulation
management in both stroke prevention and venous thromboembolism (VTE) …

A comprehensive overview of direct oral anticoagulants for the management of venous thromboembolism

AJ Comerota, E Ramacciotti - The American Journal of the Medical …, 2016 - Elsevier
Venous thromboembolism (VTE) is a prevalent, potentially fatal health problem. Although
standard anticoagulant therapy is effective when compared with the newer direct oral …

Direct oral anticoagulants in the treatment of acute venous thromboembolism: a systematic review and meta-analysis

A Gómez-Outes, AI Terleira-Fernández… - Thrombosis research, 2014 - Elsevier
Introduction Acute venous thromboembolism (VTE) is a common disease associated to
significant morbidity and mortality. Materials and methods We systematically reviewed and …

[HTML][HTML] New oral anticoagulants for the treatment of venous thromboembolism: understanding differences and similarities

PP Dobesh, J Fanikos - Drugs, 2014 - Springer
Venous thromboembolism (VTE) is a major cause of morbidity, mortality, and healthcare
expenditure. In the United States, approximately 0.1% of the population experiences an …

Evolving use of new oral anticoagulants for treatment of venous thromboembolism

CH Yeh, PL Gross, JI Weitz - … Journal of the American Society of …, 2014 - ashpublications.org
The new oral anticoagulants (NOACs), which include dabigatran, rivaroxaban, apixaban,
and edoxaban, are poised to replace warfarin for treatment of the majority of patients with …

Direct oral anticoagulants in the treatment of venous thromboembolism, with a focus on patients with pulmonary embolism: an evidence-based review

A Gómez-Outes, ML Suárez-Gea… - Vascular health and …, 2014 - Taylor & Francis
Pulmonary embolism (PE) is a relatively common cardiovascular emergency. PE and deep
vein thrombosis (DVT) are considered expressions of the same disease, termed as venous …