Circadian rhythms are endogenously-mediated 24 h cycles of behavioral or physiological
activity. The interactions among the mammalian circadian clock, acute seizures, and chronic …

Purpose: To determine the prevalence of heart rate changes and ECG abnormalities during
epileptic seizures and to determine the timing of heart rate changes compared to the first …

Epilepsy and seizures can have a dramatic effect on the autonomic nervous system by
involvement of the central autonomic control centers. The peri-ictal changes can lead to …

Electrocardiogram (ECG) recordings, lasting hours before epileptic seizures, have been
studied in the search for evidence of the existence of a preictal interval that follows a normal …

Purpose Wearable automated detection devices of focal epileptic seizures are needed to
alert patients and caregivers and to optimize the medical treatment. Heart rate variability …

The influence of the central nervous system and autonomic system on cardiac activity is
being intensively studied, as it contributes to the high rate of cardiologic comorbidities …

Many physiological processes such as sleep, hormonal secretion, or thermoregulation, are
expressed as daily rhythms orchestrated by the circadian timing system. A powerful internal …

Objective Previous studies reporting circadian patterns of epileptiform activity and seizures
are limited by (1) short‐term recording in an epilepsy monitoring unit (EMU) with altered …

People living with uncontrolled epilepsy face the constant fear of seizures. The mental toll of
anticipation and uncertainty surrounding the random occurrence of seizures may actually be …

Despite progress in the development of anti-seizure drugs, drug-resistant epilepsy (DRE)
occurs in a third of patients. DRE is associated with poor quality of life and increased risk of …