Kinetic Isomers of a Class II MHC− Peptide Complex
Class II major histocompatibility (MHC) molecules bind fragments of antigens and present
them to T cells. The triggering of the T-cell receptor (TCR) of CD4+ T-helper cells by these …
them to T cells. The triggering of the T-cell receptor (TCR) of CD4+ T-helper cells by these …
Peptide binding to MHC class I and II proteins: new avenues from new methods
R Yaneva, C Schneeweiss, M Zacharias… - Molecular immunology, 2010 - Elsevier
Major histocompatibility complex (MHC) class I and II proteins have been in the focus of
interest for immunologists, biochemists, cell biologists, and structural biologists for decades …
interest for immunologists, biochemists, cell biologists, and structural biologists for decades …
Peptide binding by class I and class II MHC molecules
MA Batalia, EJ Collins - Peptide Science, 1997 - Wiley Online Library
Major histocompatibility complex (MHC) antigens bind peptides of diverse sequences with
high affinity. They do this in order to generate maximal immunological protection by covering …
high affinity. They do this in order to generate maximal immunological protection by covering …
Effects of peptide length and composition on binding to an empty class I MHC heterodimer
ML Fahnestock, JL Johnson, RMR Feldman… - Biochemistry, 1994 - ACS Publications
Revised Manuscript Received April 11, 1994® abstract: Class I major histocompatibility
complex (MHC) proteins present peptide antigens to T cells during the immune response …
complex (MHC) proteins present peptide antigens to T cells during the immune response …
Defining rules for the peptide-MHC class II interaction
F Sinigaglia, J Hammer - Current opinion in immunology, 1994 - Elsevier
Recent work has begun to clarify the molecular events governing peptide interaction with
MHC class II proteins. The requirements for peptide binding to class I and class II molecules …
MHC class II proteins. The requirements for peptide binding to class I and class II molecules …
Major histocompatibility complex class II binding characteristics of peptoid–peptide hybrids
EC de Haan, MHM Wauben… - Bioorganic & medicinal …, 2002 - Elsevier
The major histocompatibility complex (MHC) class II binding requirements for solvent-
exposed peptide residues were systematically studied using amino acid and peptoid …
exposed peptide residues were systematically studied using amino acid and peptoid …
Crystal structures of HLA‐A* 0201 complexed with antigenic peptides with either the amino‐or carboxyl‐terminal group substituted by a methyl group
M Bouvier, HC Guo, KJ Smith… - … : Structure, Function, and …, 1998 - Wiley Online Library
The crystal structures of class I major histocompatibility complex (MHC) molecules
complexed with antigenic peptides revealed a network of hydrogen bonds between the …
complexed with antigenic peptides revealed a network of hydrogen bonds between the …
Conformational heterogeneity of MHC class II induced upon binding to different peptides is a key regulator in antigen presentation and epitope selection
S Sadegh-Nasseri, S Natarajan, CL Chou… - Immunologic …, 2010 - Springer
T cells bearing αβ receptors recognize antigenic peptides bound to class I and class II
glycoproteins encoded in the major histocompatibility complex (MHC). Cytotoxic and helper …
glycoproteins encoded in the major histocompatibility complex (MHC). Cytotoxic and helper …
Altered peptide ligand design: altering immune responses to class I MHC/peptide complexes
EJ Collins, JA Frelinger - Immunological reviews, 1998 - Wiley Online Library
Class I proteins are responsible for binding proteins from endogenously synthesized
proteins and displaying them on the cell surface. Our understanding of this process has …
proteins and displaying them on the cell surface. Our understanding of this process has …
The Carboxy Terminus of the Ligand Peptide Determines the Stability of the MHC Class I Molecule H-2Kb: A Combined Molecular Dynamics and Experimental Study
Major histocompatibility complex (MHC) class I molecules (proteins) bind peptides of eight to
ten amino acids to present them at the cell surface to cytotoxic T cells. The class I binding …
ten amino acids to present them at the cell surface to cytotoxic T cells. The class I binding …