The pyramidal neurons of the mammalian neocortex form two major types of long-range
connections—corticocortical and cortico-subcortical. The transcription factors Satb2 and …

Satb2 is a DNA-binding protein that regulates chromatin organization and gene expression.
In the developing brain, Satb2 is expressed in cortical neurons that extend axons across the …

The acquisition of distinct neuronal fates is fundamental for the function of the cerebral
cortex. We find that the development of subcerebral projections from layer 5 neurons in the …

Pyramidal neurons of the neocortex can be subdivided into two major groups: deep-(DL)
and upper-layer (UL) neurons. Here we report that the expression of the AT-rich DNA …

The molecular linkage between neocortical projection neuron subtype and area
development, which enables the establishment of functional areas by projection neuron …

While transcriptional controls over the size and relative position of cortical areas have been
identified, less is known about regulators that direct acquisition of area-specific …

The left and right sides of the nervous system communicate via commissural axons that
cross the midline during development using evolutionarily conserved molecules. These …

Recent studies have demonstrated that the topography of thalamocortical (TC) axon
projections is initiated before they reach the cortex, in the ventral telencephalon (VTel) …

The cerebellum receives its input from multiple precerebellar nuclei located in the brainstem
and sends processed information to other brain structures via the deep cerebellar neurons …

During neocortical development, neurons undergo polarization, oriented migration, and
layer-type-specific differentiation. The transcriptional programs underlying these processes …