Susceptibility to the respiratory effects of air pollution varies between individuals. Although
some evidence suggests higher susceptibility for subjects carrying variants of antioxidant …

Oxidative stress occurs when antioxidant defences, which are regulated by a complex
network of genes, are insufficient to maintain the level of reactive oxygen species below a …

Chronic exposure to ozone (O3) can cause changes in lung function that may reflect
remodelling of small airways. It is likely that antioxidant enzyme function affects susceptibility …

Abstract Purpose of Review The purpose of this review is to summarize the evidence from
recently published original studies investigating how glutathione S-transferase (GST) gene …

There is large variation between individuals in their response to air pollutants. This review
summarises the existing evidence that genetic factors influence the mechanisms of lung …

Objective: The objective of this article is to evaluate genetic risks associated with the
pulmonary response to air pollutants, including particulates and ozone. Methods: A …

Background: Observational epidemiological studies of dietary antioxidant intake, serum
antioxidant concentration and lung outcomes suggest that lower levels of antioxidant …

Dietary antioxidants may protect lung tissue against reactive oxygen species-induced injury,
adverse respiratory effects and reduced pulmonary function. Genetic variability in …

Oxidative stress is believed to play an important role in the pathogenesis of smoking-
induced chronic obstructive pulmonary disease. We hypothesized that polymorphisms of …

Abstract Purpose of Review Glutathione S-transferase (GST) genes are involved in oxidative
stress management and may modify the impact of indoor air pollution. We aimed to assess …