Biology of nitrogen oxides in the gastrointestinal tract

JO Lundberg, E Weitzberg - Gut, 2013 - gut.bmj.com
Throughout the human gastrointestinal tract a variety of reactive nitrogen oxides are
continuously formed as a result of a complex interplay between the host, commensal …

Nitric oxide in gastrointestinal health and disease

V Shah, G Lyford, G Gores, G Farrugia - Gastroenterology, 2004 - Elsevier
Nitric oxide is an intracellular and intercellular messenger with important functions in a
number of physiologic and pathobiologic processes within gastroenterology and …

III. A molecular prelude to intestinal inflammation

MJS Miller, M Sandoval - American Journal of Physiology …, 1999 - journals.physiology.org
Nitric oxide (NO) synthesis is markedly augmented in states of inflammation, largely due to
the expression of inducible nitric oxide synthase (iNOS). Although NO has anti-inflammatory …

Role of nitric oxide in gastrointestinal inflammatory and ulcerative diseases: perspective for drugs development

MD Barrachina, J Panes… - Current pharmaceutical …, 2001 - ingentaconnect.com
Nitric oxide is a ubiquitous molecule involved in a variety of biological processes. The
specific action of NO depends on its enzymatic sources namely neuronal nitric oxide …

Intragastric nitration by dietary nitrite: implications for modulation of protein and lipid signaling

BS Rocha, B Gago, RM Barbosa, JO Lundberg… - Free Radical Biology …, 2012 - Elsevier
Inorganic nitrite, derived from the reduction of nitrate in saliva, has recently emerged as a
protagonist in nitric oxide (• NO) biology as it can be univalently reduced to• NO, in the …

Nitric oxide in the gut.

AL Salzman - New horizons (Baltimore, Md.), 1995 - europepmc.org
Nitric oxide (NO.) plays a central role in the physiology of the gastrointestinal tract and its
response to critical illness. Potential sources of NO. in the gut include: intrinsic intestinal …

Nitric oxide in the gastrointestinal tract: opportunities for drug development

JL Wallace - British journal of pharmacology, 2019 - Wiley Online Library
Nitric oxide (NO) plays important roles in gastrointestinal mucosal defence, as well as in the
pathogenesis of several gastrointestinal diseases (eg irritable bowel syndrome and …

Nitric oxide: a regulator of mucosal defense and injury

SN Elliott, JL Wallace - Journal of gastroenterology, 1998 - Springer
There is an abundance of evidence that nitric oxide plays a critical role in regulating several
components of gastrointestinal mucosal defense. Suppression of nitric oxide synthesis …

Nitric oxide and intestinal inflammation

P Kubes, DM McCafferty - The American journal of medicine, 2000 - Elsevier
Inflammation of the intestinal tract remains a very serious concern in the clinical setting.
Unfortunately, to date, the mechanisms underlying many inflammatory conditions such as …

Nitric oxide-a mediator of inflammation or mucosal defence

BJR Whittle - European journal of gastroenterology & hepatology, 1997 - journals.lww.com
Nitric oxide (NO) can exert both protective and proinflammatory actions in the
gastrointestinal tract. NO, formed physiologically by constitutive NO synthases, regulates …