Children with sickle cell anemia (HbSS) are at high risk for neurologically overt cerebral
infarcts associated with stroke and neurologically silent cerebral infarcts correlated with …

Background A substantial minority of neurologically normal children with sickle cell disease
have lesions consistent with cerebral infarction as seen on magnetic resonance imaging …

Objective: To determine whether children with homozygous sickle cell anemia (SCD) who
have silent infarcts on magnetic resonance imaging (MRI) of the brain are at increased risk …

Children with sickle cell disease (SCD) and strokes receive blood transfusion therapy for
secondary stroke prevention; despite this, approximately 20% experience second overt …

Silent cerebral infarct (SCI) is the most common form of neurologic disease in children with
sickle cell anemia (SCA). SCI is defined as abnormal magnetic resonance imaging (MRI) of …

Cerebral infarction is a common complication of sickle cell disease and may manifest as
overt stroke or cognitive impairment associated with “silent” cerebral infarction on magnetic …

Objective. Brain magnetic resonance imaging (MRI) and neuropsychological evaluations
were conducted to determine whether neuroradiographic evidence of infarct in children with …

Background. Silent infarcts have been reported in 17% of young patients with sickle cell
disease and are associated with impaired performance on standardized psychometric tests …

BACKGROUND AND PURPOSE: Children with hemoglobin SS sickle cell disease are
known to suffer cognitive impairment if they have silent infarct, but recent evidence suggests …

Background Silent cerebral infarcts are the most common neurologic injury in children with
sickle cell anemia and are associated with the recurrence of an infarct (stroke or silent …