[en] The study of long-term effects of therapy for childhood cancer is important for several
reasons. An increasing proportion of children are now cured of their cancer and can expect …

In the last four decades, advances in therapies for primary cancers have improved overall
survival for childhood cancer. Currently, almost 80% of children will survive beyond 5 years …

The child appears more sensitive than the adult to the carcinogenic effects of radiation for
certain sites such as the breast and thyroid. However, there are few studies of persons who …

With improvements in survival among individuals diagnosed and treated for cancer there is
an increasing recognition of the risk of long-term adverse effects of therapy. Second …

Objectives The majority of childhood cancer patients now achieve long-term survival, but the
treatments that cured their malignancy often put them at risk of adverse health outcomes …

A new malignancy was diagnosed in 19 of 414 long‐term survivors of cancer in childhood.
All but two lesions were attributable to prior radiotherapy; eight were successfully treated …

Radiation-induced heritable diseases have not been demonstrated in humans and
estimates of genetic risks for protection purposes are based on mouse experiments. The …

Purpose The projected existence and magnitude of carcinogenic effects of ionizing radiation
at low doses and low-dose rates is perhaps the most important issue in radiation protection …

As the population of cancer survivors has increased and continues to age, the occurrence of
second cancers has risen dramatically-from 9% of all cancer diagnoses in 1975-1979 to …

Survival of children diagnosed with cancer has improved markedly, because of
improvements in chemotherapy and radiation treatment protocols, better diagnosis, and risk …