Polycaprolactone-gelatin membrane as a sealant biomaterial efficiently prevents postoperative anastomotic leakage with promoting tissue repair

G Joo, T Sultana, S Rahaman, SH Bae… - Journal of …, 2021 - Taylor & Francis
Anastomotic leakage due to post-surgical suture line disruption is one of the crucial factors
affecting patient's survival and quality of life. To resolve the poor healing of surgical …

Gelatinized PLCL Electrospun Membrane for the Prevention of Postoperative Abdominal Adhesion Through Fibrinolysis Activation

R Gao, P Kong, C Yang, X Liu, J Wang… - Advanced Materials …, 2022 - Wiley Online Library
Abdominal adhesion is a common complication after surgery, which causes pain to patient
and increases the risks of reoperation. Electrospinning polyester membrane serving as a …

Evaluation of the potential anti‐adhesion effect of the PVA/Gelatin membrane

SH Bae, SR Son, S Kumar Sakar… - … Research Part B …, 2014 - Wiley Online Library
ABSTRACT A common and prevailing complication for patients with abdominal surgery is
the peritoneal adhesion that follows during the post‐operative recovery period …

Prevention of intra-abdominal adhesion using electrospun PEG/PLGA nanofibrous membranes

J Li, J Zhu, T He, W Li, Y Zhao, Z Chen, J Zhang… - Materials Science and …, 2017 - Elsevier
The use of physical barriers, such as nanofiber membranes, is a potential method to prevent
adhesion formation after surgery. In this study, we fabricated electrospun composite poly …

Elastic/adhesive double-layered PLA-PEG multiblock copolymer membranes for postoperative adhesion prevention

T Yamaoka, E Njatawidjaja, A Kasai… - … degradation and stability, 2013 - Elsevier
Tissue adhesions cause severe and life-threatening conditions, including pain, infertility,
and heart defects. The purpose of this study is to develop an anti-adhesion membrane that …

Function of poly (lactic-co-glycolic acid) nanofiber in reduction of adhesion bands

P Dinarvand, SM Hashemi, E Seyedjafari… - Journal of Surgical …, 2012 - Elsevier
BACKGROUND: In this study, we investigated the anti-adhesive and anti-inflammatory
effects of electrospun nanofibrous membranes made of polycaprolactone (PCL), poly-L …

Tissue-sealing and anti-adhesion properties of an in situ hydrogel of hydrophobically-modified Alaska pollock-derived gelatin

Y Mizuno, S Watanabe, T Taguchi - International Journal of Biological …, 2020 - Elsevier
Anastomotic leakage and tissue adhesion are significant complications associated with
colorectal surgeries, such as the resection of colorectal cancer. However, an effective …

Preparation and characterization of biodegradable anti-adhesive membrane for peritoneal wound healing

SN Park, HJ Jang, YS Choi, JM Cha, SY Son… - Journal of Materials …, 2007 - Springer
Postoperative adhesions remain a significant complication of abdominal surgery although
the wide variety of physical barriers has been developed to reduce the incidence of …

Evaluation of an octyl group-modified Alaska pollock gelatin-based surgical sealant for prevention of postoperative adhesion

R Mizuta, Y Mizuno, X Chen, Y Kurihara, T Taguchi - Acta biomaterialia, 2021 - Elsevier
Postoperative adhesion can lead to an increase in the number of surgeries required, longer
operation times, and high medical costs, resulting in the quality of life of the patient being …

Bilateral PLA/alginate membranes for the prevention of postsurgical adhesions

M Kessler, E Esser, J Groll… - Journal of Biomedical …, 2016 - Wiley Online Library
A bilateral barrier membrane for the prevention of postsurgical adhesions was developed.
Thereby, a smooth PLA side was supposed to keep the affected tissues glidingly separated …