The central nervous system (CNS) is considered to be immune privileged, owing in part to
the absence of major histocompatibility (MHC) class II+ cells in the healthy brain …

There are numerous observations reporting that phagocytes expressing major
histocompatibility complex (MHC) Class II molecules are associated with the central nervous …

Although the brain is now known to actively interact with the immune system under non-
inflammatory conditions, the site of cell–cell interactions between brain parenchymal cells …

Murine studies have highlighted a crucial role for immune cells in the meninges in
surveilling the central nervous system (CNS) and influencing neuroinflammation. However …

Microglial cells form a network of potential antigen presenting cells throughout the nervous
system. Much progress has recently been made towards a better understanding of their …

The infiltration of immune cells in the central nervous system is a common hallmark in
different neuroinflammatory conditions. Accumulating evidence indicates that resident glial …

Simple Summary In the central nervous system, immune cells can be broadly categorized as
parenchymal microglia or non-parenchymal border-associated macrophages. It has become …

Recent murine studies have highlighted a crucial role for the meninges in surveilling the
central nervous system (CNS) and influencing CNS inflammation. However, how meningeal …

Microglia are central nervous system (CNS) resident immune cells for which the impact of
MHC class I antigen presentation is still being defined. To directly address if microglia …

The central nervous system (CNS) and its meningeal coverings accommodate a diverse
myeloid compartment that includes parenchymal microglia and perivascular macrophages …