The significance of placenta growth factor in angiogenesis and clinical outcome of human gastric cancer

CN Chen, FJ Hsieh, YM Cheng, WF Cheng, YN Su… - Cancer letters, 2004 - Elsevier
Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF)
family of proangiogenic factors and its overexpression has been linked to pathological …

Placenta growth factor is over-expressed and has prognostic value in human breast cancer

C Parr, G Watkins, M Boulton, J Cai… - European Journal of …, 2005 - Elsevier
Placenta growth factor (PlGF) belongs to the vascular endothelial growth factor (VEGF)
family, a group of angiogenic factors that are crucial for tumour angiogenesis. Very little is …

Placenta growth factor expression is correlated with survival of patients with colorectal cancer

SC Wei, PN Tsao, SC Yu, CT Shun, JJ Tsai-Wu… - Gut, 2005 - gut.bmj.com
Background: Overexpression of vascular endothelial growth factor (VEGF) correlates with
vascularity, metastasis, and proliferation in colorectal cancer but the role of its homologue …

[PDF][PDF] Placenta growth factor is abundantly expressed in human cervical squamous cell carcinoma.

J Kodama, N Seki, K Tokumo, Y Nakanishi… - Placenta, 1997 - article.imrpress.com
Tumor angiogenesis is essential for solid tumor growth. The object of this study was to
investigate the presence of newly identified angiogenic factor, placenta growth factor (P1GF) …

Tumor cell-derived placental growth factor sensitizes antiangiogenic and antitumor effects of anti-VEGF drugs

EME Hedlund, X Yang, Y Zhang… - Proceedings of the …, 2013 - National Acad Sciences
The role of placental growth factor (PlGF) in modulation of tumor angiogenesis and tumor
growth remains an enigma. Furthermore, anti-PlGF therapy in tumor angiogenesis and …

Upregulation of vascular endothelial growth factor (VEGF) and downregulation of placenta growth factor (PlGF) associated with malignancy in human thyroid tumors …

G Viglietto, D Maglione, M Rambaldi, J Cerutti… - Oncogene, 1995 - europepmc.org
Vascular endothelial growth factor (VEGF) is a potent mitogen for endothelial cells in vitro,
promotes neoangiogenesis in vivo and increases the permeability of the vascular …

Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers

A Eriksson, R Cao, R Pawliuk, SM Berg, M Tsang… - Cancer cell, 2002 - cell.com
Tumor growth and metastasis require concomitant growth of new blood vessels, which are
stimulated by angiogenic factors, including vascular endothelial growth factor (VEGF) …

PlGF knockdown inhibited tumor survival and migration in gastric cancer cell via PI3K/Akt and p38MAPK pathways

H Akrami, F Mahmoodi, S Havasi… - Cell biochemistry and …, 2016 - Wiley Online Library
The molecular signalling of placental growth factor (PlGF), a member of the vascular
endothelial growth factor family, was not uncovered in human adenocarcinoma gastric cell …

Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer …

AP Taylor, DM Goldenberg - Molecular cancer therapeutics, 2007 - AACR
The angiogenic growth factor placenta growth factor (PlGF) is implicated in several
pathologic processes, including the growth and spread of cancer. We found by …

Increased melanoma growth and metastasis spreading in mice overexpressing placenta growth factor

M Marcellini, N De Luca, T Riccioni, A Ciucci… - The American journal of …, 2006 - Elsevier
Placenta growth factor (PlGF), a member of the vascular endothelial growth factor family,
plays an important role in adult pathological angiogenesis. To further investigate PlGF …