The scarcity of transplant allografts for diseased organs has prompted efforts at tissue
regeneration using seeded scaffolds, an approach hampered by the enormity of cell types …

The use of stem cells has enabled the successful generation of simple organs. However,
anatomically complicated organs such as the kidney have proven more refractory to stem …

Introduction To address transplant organ shortage, a promising strategy is to decellularize
kidneys in a manner that the scaffold retains signals for seeded pluripotent precursor cells to …

For chronic kidney diseases, there is little chance that the vast majority of world's population
will have access to renal replacement therapy with dialysis or transplantation. Tissue …

Abstract (Re) Building a Kidney is a National Institute of Diabetes and Digestive and Kidney
Diseases-led consortium to optimize approaches for the isolation, expansion, and …

Despite the enthusiasm for bioengineering of functional renal tissues for transplantation,
many obstacles remain before the potential of this technology can be realized in a clinical …

The shortage of transplantable organs provides an impetus to develop tissue-engineered
alternatives. Producing tissues similar to immature kidneys from simple suspensions of fully …

Tissue engineering and cell therapy approaches aim to take advantage of the repopulating
ability and plasticity of multipotent stem cells to regenerate lost or diseased tissue. Recently …

As one of the major components of regenerative medicine, tissue engineering follows the
principles of cell transplantation, materials science, and engineering toward the …

Human pluripotent stem cell (hPSC)-derived kidney organoids may facilitate disease
modeling and the generation of tissue for renal replacement. Long-term application …